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Name | Hydroxycarboxylic acid receptor 2 |
---|---|
Species | Mus musculus (Mouse) |
Gene | Hcar2 |
Synonym | Protein PUMA-G Nicotinic acid receptor Nic1 Niacr1 niacin receptor 1 [ Show all ] |
Disease | N/A for non-human GPCRs |
Length | 360 |
Amino acid sequence | MSKSDHFLVINGKNCCVFRDENIAKVLPPVLGLEFVFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLIICLPFLTDNYVHNWDWRFGGIPCRVMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHFLNKISNRTAAIISCFLWGLTIGLTVHLLYTNMMTKNGEAYLCSSFSICYNFRWHDAMFLLEFFLPLAIILFCSGRIIWSLRQRQMDRHAKIKRAINFIMVVAIVFIICFLPSVAVRIRIFWLLYKYNVRNCDIYSSVDLAFFTTLSFTYMNSMLDPVVYYFSSPSFPNFFSTCINRCLRKKTLGEPDNNRSTSVELTGDPSTTRSIPGALMADPSEPGSPPYLASTSR |
UniProt | Q9EP66 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL4420 |
IUPHAR | 312 |
DrugBank | N/A |
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GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
12520 | SCH-900271 | C14H16N2O4 | 276.292 | 4 / 2 | 1.6 | Yes |
30297 | CHEMBL519689 | C14H14N6 | 266.308 | 4 / 2 | 1.9 | Yes |
31427 | CHEMBL1672639 | C15H16F2N2O3 | 310.301 | 6 / 1 | 2.7 | Yes |
558611 | MK-6892 | C19H22N4O5 | 386.408 | 8 / 3 | 2.3 | Yes |
53193 | CHEMBL2036951 | C11H10F2N2O4 | 272.208 | 6 / 2 | 0.6 | Yes |
58659 | CHEMBL1671877 | C14H14F2N2O3 | 296.274 | 6 / 1 | 2.3 | Yes |
67178 | CHEMBL482943 | C13H11FN6 | 270.271 | 5 / 2 | 1.6 | Yes |
75355 | 5932-32-1 | C7H8N2O2 | 152.153 | 3 / 2 | 0.8 | Yes |
75851 | CHEMBL502716 | C13H11ClN6 | 286.723 | 4 / 2 | 2.2 | Yes |
101744 | CHEMBL1208920 | C10H14N2O2 | 194.234 | 3 / 2 | 2.0 | Yes |
102619 | CHEMBL504980 | C13H11FN6 | 270.271 | 5 / 2 | 1.6 | Yes |
560516 | 2-(3-(3-(4-hydroxyphenyl)-1,2,4-oxadiazol-5-yl)propanamido)benzoic acid | C18H15N3O5 | 353.334 | 7 / 3 | 2.6 | Yes |
116500 | CHEMBL520137 | C13H9F3N6 | 306.252 | 7 / 2 | 1.8 | Yes |
116665 | CHEMBL2036813 | C11H12N2O4 | 236.227 | 4 / 2 | 0.7 | Yes |
128698 | CHEMBL1208922 | C13H12N2O2 | 228.251 | 3 / 2 | 2.2 | Yes |
132115 | CHEMBL1208919 | C10H14N2O2 | 194.234 | 3 / 2 | 2.3 | Yes |
132473 | CHEMBL483141 | C13H10F2N6 | 288.262 | 6 / 2 | 1.7 | Yes |
135351 | CHEMBL483142 | C13H10F2N6 | 288.262 | 6 / 2 | 1.7 | Yes |
135930 | CHEMBL1208921 | C11H16N2O2 | 208.261 | 3 / 2 | 2.5 | Yes |
145988 | CHEMBL447050 | C13H11ClN6 | 286.723 | 4 / 2 | 2.2 | Yes |
148426 | CHEMBL2036954 | C13H14N2O4 | 262.265 | 4 / 2 | 1.2 | Yes |
169205 | CHEMBL519966 | C13H11FN6 | 270.271 | 5 / 2 | 1.6 | Yes |
178934 | CHEMBL482979 | C12H18N6 | 246.318 | 4 / 2 | 2.8 | Yes |
193895 | CHEMBL485195 | C13H11ClN6 | 286.723 | 4 / 2 | 2.2 | Yes |
196139 | MK-0354 | C7H8N6 | 176.183 | 4 / 2 | 0.2 | Yes |
196370 | CHEMBL507182 | C13H10F2N6 | 288.262 | 6 / 2 | 1.7 | Yes |
205766 | CHEMBL519811 | C13H10F2N6 | 288.262 | 6 / 2 | 1.7 | Yes |
222186 | 6-METHYL-1,4,5,6-TETRAHYDROCYCLOPENTAPYRAZOLE-3-CARBOXYLIC ACID | C8H10N2O2 | 166.18 | 3 / 2 | 1.1 | Yes |
228525 | CHEMBL1208925 | C11H10N2O2S | 234.273 | 4 / 2 | 1.8 | Yes |
244676 | CHEMBL520676 | C13H10F2N6 | 288.262 | 6 / 2 | 1.7 | Yes |
262440 | CHEMBL485194 | C14H14N6 | 266.308 | 4 / 2 | 1.9 | Yes |
269963 | nicotinic acid | C6H5NO2 | 123.111 | 3 / 1 | 0.4 | Yes |
299144 | CHEMBL1208923 | C13H9F3N2O2 | 282.222 | 6 / 2 | 2.5 | Yes |
299294 | CHEMBL501585 | C10H12N6 | 216.248 | 4 / 2 | 1.2 | Yes |
302709 | CHEMBL520675 | C13H12N6 | 252.281 | 4 / 2 | 1.5 | Yes |
311966 | CHEMBL519338 | C9H12N6 | 204.237 | 4 / 2 | 1.1 | Yes |
312505 | CHEMBL1208987 | C10H10N4O2 | 218.216 | 4 / 2 | 0.4 | Yes |
313136 | CHEMBL1208924 | C11H10N2O2S | 234.273 | 4 / 2 | 1.9 | Yes |
347047 | CHEMBL509541 | C11H16N6 | 232.291 | 4 / 2 | 2.2 | Yes |
356079 | CHEMBL1208988 | C9H9N5O2 | 219.204 | 5 / 2 | -0.2 | Yes |
358266 | CHEMBL484172 | C13H20N6 | 260.345 | 4 / 2 | 3.3 | Yes |
373068 | CHEMBL500239 | C10H14N6 | 218.264 | 4 / 2 | 1.7 | Yes |
555152 | (R)-3-Hydroxybutanoic acid | C4H8O3 | 104.105 | 3 / 2 | -0.5 | Yes |
404227 | CHEMBL1208926 | C11H12N4O2 | 232.243 | 4 / 2 | 0.5 | Yes |
411070 | CHEMBL520159 | C12H16N6 | 244.302 | 4 / 2 | 2.2 | Yes |
423684 | CHEMBL1208986 | C11H12N4O2 | 232.243 | 4 / 2 | 0.5 | Yes |
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