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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1208986
Molecular formula	C11H12N4O2
IUPAC name	5-(2-methylpyrazol-3-yl)-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carboxylic acid
Molecular weight	232.243
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	0.5
Synonyms	compound 8f [PMID: 20615702] SCHEMBL13935754 5-(1-methyl-1H-pyrazol-5-yl)-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carboxylic acid D06WXN 5-(2-methylpyrazol-3-yl)-1,4,5,6-tetrahydrocyclopenta[d]pyrazole-3-carboxylic acid GTPL5793 BDBM50323398 [ Show all ]
Inchi Key	ZAJBYTSUTBCMRM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C11H12N4O2/c1-15-9(2-3-12-15)6-4-7-8(5-6)13-14-10(7)11(16)17/h2-3,6H,4-5H2,1H3,(H,13,14)(H,16,17)
PubChem CID	12003694
ChEMBL	CHEMBL1208986
IUPHAR	5793
BindingDB	50323398
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
423683	Hydroxycarboxylic acid receptor 2	Q8TDS4	HCAR2	Homo sapiens (Human)	363
423684	Hydroxycarboxylic acid receptor 2	Q9EP66	Hcar2	Mus musculus (Mouse)	360

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