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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1672639
Molecular formula	C15H16F2N2O3
IUPAC name	2-(difluoromethyl)-5-[3-(1-methylcyclopropyl)propyl]-3H-pyrano[2,3-d]pyrimidine-4,7-dione
Molecular weight	310.301
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	2.7
Synonyms	BDBM50337024 SCHEMBL12560485 2-(difluoromethyl)-5-(3-(1-methylcyclopropyl)propyl)-3H-pyrano[2,3-d]pyrimidine-4,7-dione
Inchi Key	BRWOJXBDKLPQCT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C15H16F2N2O3/c1-15(5-6-15)4-2-3-8-7-9(20)22-14-10(8)13(21)18-12(19-14)11(16)17/h7,11H,2-6H2,1H3,(H,18,19,21)
PubChem CID	24955646
ChEMBL	CHEMBL1672639
IUPHAR	N/A
BindingDB	50337024
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
31427	Hydroxycarboxylic acid receptor 2	Q9EP66	Hcar2	Mus musculus (Mouse)	360
31428	Hydroxycarboxylic acid receptor 2	Q80Z39	Hcar2	Rattus norvegicus (Rat)	360
31429	Hydroxycarboxylic acid receptor 2	Q8TDS4	HCAR2	Homo sapiens (Human)	363
31430	Hydroxycarboxylic acid receptor 3	P49019	HCAR3	Homo sapiens (Human)	387

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