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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SIB 1757
Molecular formula	C12H11N3O
IUPAC name	6-methyl-2-phenyldiazenylpyridin-3-ol
Molecular weight	213.24
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	3.0
Synonyms	HMS3267D07 MolPort-003-959-633 NSC_5218788 SMR000326907 ZINC18155387 AC1O3ID7 BRD-K98157055-001-04-2 CTK1B2569 L000560 NCGC00025047-02 SCHEMBL179770 SR-01000076142-3 31993-01-8 AKOS024456470 CHEBI:93722 DTXSID00425754 LP01161 NCGC00185991-01 SIB-1757 ZINC100001934 (2Z)-6-methyl-2-(phenylhydrazinylidene)pyridin-3-one 6-methyl-2-[(E)-phenyldiazenyl]pyridin-3-ol BDBM86717 CHEMBL405358 HMS2231C22 HMS3369P05 NCGC00015978-01 S 9186 SR-01000076142 3-Pyridinol, 6-methyl-2-(2-phenyldiazenyl)- AC1O44IY CAS_5218788 D05TFE Lopac-S-9186 NCGC00025047-03 Tocris-1215 6-Methyl-2-(phenylazo)-3-pyridinol B6636 EU-0101161 MLS000860049 NCGC00261846-01 SIB1757 ZINC13557614 (E)-6-methyl-2-(phenyldiazenyl)pyridin-3-ol BN0481 CHEMBL88553 HMS3263J03 J-018594 NCGC00025047-01 SCHEMBL10160623 SR-01000076142-1 3-Pyridinol, 6-methyl-2-(phenylazo)- AC1OBJF8 CCG-205235 D0Q6VH Lopac0_001161 NCGC00025047-04 SIB 1757, >=99% (HPLC), crystalline Tox21_501161 (2E)-6-methyl-2-(phenylhydrazinylidene)pyridin-3-one 6-methyl-2-(phenylhydrazinylidene)pyridin-3-one BC600132 CHEMBL1427311 GTPL1431 [ Show all ]
Inchi Key	LOCPVWIREQIGNQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C12H11N3O/c1-9-7-8-11(16)12(13-9)15-14-10-5-3-2-4-6-10/h2-8,16H,1H3
PubChem CID	5218788
ChEMBL	CHEMBL1427311
IUPHAR	N/A
BindingDB	86717
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
563357	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
563361	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
563360	Metabotropic glutamate receptor 3	Q14832	GRM3	Homo sapiens (Human)	879
563365	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
563356	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
563358	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203
563364	Metabotropic glutamate receptor 6	O15303	GRM6	Homo sapiens (Human)	877
563362	Metabotropic glutamate receptor 7	Q14831	GRM7	Homo sapiens (Human)	915
563359	Metabotropic glutamate receptor 8	O00222	GRM8	Homo sapiens (Human)	908
563363	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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