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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SB 242084
Molecular formula	C21H19ClN4O2
IUPAC name	6-chloro-5-methyl-N-[6-(2-methylpyridin-3-yl)oxypyridin-3-yl]-2,3-dihydroindole-1-carboxamide
Molecular weight	394.859
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	3.8
Synonyms	L000542 SB-242,084 AB0089377 D00EMF PDSP1_001569 SCHEMBL507945 1H-Indole-1-carboxamide, 6-chloro-2,3-dihydro-5-methyl-N-(6-((2-methyl-3-pyridinyl)oxy)-3-pyridinyl)- AKOS032945733 GTPL193 6-chloro-5-methyl-N-[6-(2-methylpyridin-3-yl)oxypyridin-3-yl]-2,3-dihydroindole-1-carboxamide BDBM85097 NCGC00186029-01 SB-242084 1215566-78-1 AC1MUPO0 CHEMBL14563 DTXSID70394600 PDSP2_001553 ZINC602170 6-Chloro-2,3-dihydro-5-methyl-N-[6-[(2-methyl-3-pyridinyl)oxy]-3-pyridinyl]-1H-indole-1-carboxamide Dihydrochloride Hydrate API0006977 HY-13409 SB 242084 hydrochloride CAS_181632-25-7 NCGC00186029-02 SB242084 AJ-23679 CS-4329 EX-A2270 S-7715 6-chloro-5-methyl-1-((2-(2-methylpyrid-3-yloxy)pyrid-5-yl)carbamoyl)indoline BCP07316 [ Show all ]
Inchi Key	GIUZEIJUFOPTMR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H19ClN4O2/c1-13-10-15-7-9-26(18(15)11-17(13)22)21(27)25-16-5-6-20(24-12-16)28-19-4-3-8-23-14(19)2/h3-6,8,10-12H,7,9H2,1-2H3,(H,25,27)
PubChem CID	3644637
ChEMBL	CHEMBL14563
IUPHAR	193
BindingDB	85097
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
97599	5-hydroxytryptamine receptor 1B	P46636	HTR1B	Cricetulus griseus (Chinese hamster)	386
97594	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
524384	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
97597	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
97598	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
524385	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460
97596	5-hydroxytryptamine receptor 4	Q29006	HTR4	Sus scrofa (Pig)	137
555837	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
97600	Alpha-1B adrenergic receptor	P18841	ADRA1B	Mesocricetus auratus (Golden hamster)	515
97595	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446

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