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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL334014
Molecular formula	C8H10FNO4
IUPAC name	(1S,2S,3S,5R,6S)-2-amino-3-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Molecular weight	203.169
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	-3.2
Synonyms	(1s,2s,3s,5r,6s)-2-amino-3-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid CTK1A0318 MGS-0008 (+)-2-Amino-3-fluoro-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid 2-Amino-3-fluoro-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid DIWVNJFXRKZAGI-FJNNMDBYSA-N BDBM50094841 SCHEMBL2454834 (-)-2-Amino-3-fluoro-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid 234085-20-2 DTXSID50431168 Bicyclo[3.1.0]hexane-2,6-dicarboxylicacid, 2-amino-3-fluoro-, (1S,2S,3S,5R,6S)- [ Show all ]
Inchi Key	DIWVNJFXRKZAGI-FJNNMDBYSA-N
Inchi ID	InChI=1S/C8H10FNO4/c9-3-1-2-4(6(11)12)5(2)8(3,10)7(13)14/h2-5H,1,10H2,(H,11,12)(H,13,14)/t2-,3-,4-,5-,8-/m0/s1
PubChem CID	9815616
ChEMBL	CHEMBL334014
IUPHAR	N/A
BindingDB	50094841
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
61159	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
61155	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
61157	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
61160	Metabotropic glutamate receptor 3	P31422	Grm3	Rattus norvegicus (Rat)	879
61161	Metabotropic glutamate receptor 3	Q14832	GRM3	Homo sapiens (Human)	879
61162	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
61156	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
61164	Metabotropic glutamate receptor 6	O15303	GRM6	Homo sapiens (Human)	877
61158	Metabotropic glutamate receptor 7	Q14831	GRM7	Homo sapiens (Human)	915
61163	Metabotropic glutamate receptor 8	O00222	GRM8	Homo sapiens (Human)	908

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