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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
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Ligand

Name	Etorphine
Molecular formula	C25H33NO4
IUPAC name	(1R,2S,6R,14R,15R,19R)-19-[(2R)-2-hydroxypentan-2-yl]-15-methoxy-5-methyl-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11,16-tetraen-11-ol
Molecular weight	411.542
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	3.1
Synonyms	Etorphine [INN:BAN] Tetrahydro-7-alpha-(1-hydroxy-1-methylbutyl)-6,14-endo-ethenooripavine 14521-96-1 6,14-Ethenomorphinan-7-methanol, 4,5-epoxy-3-hydroxy-6-methoxy-alpha,17-dimethyl-a-propyl-, [5alpha,7alpha(R)]- BDBM50123599 M. 99 [as hydrochloride] ZINC5561290 42M2Y6NU9O 6,7,8,14-Tetrahydro-7alpha-(1-hydroxy-1-methylbutyl)-6,14-endo-ethenooripavine DEA No. 9056 Propylorvinol (-)-Etorphine 6,14-endo-Ethenotetrahydrooripavine, 7alpha-((R)-1-hydroxy-1-methylbutyl)- (8CI) 95688-04-3 Etorphinum Tetrahydro-7-alpha-(2-hydroxy-2-pentyl)-6,14-endo-ethenooripavine 19-Propylorvinol 6,14-Ethenomorphinan-7-methanol, 4,5-epoxy-3-hydroxy-6-methoxy-alpha,17-dimethyl-alpha-propyl-, (5alpha,7alpha(R))- M99 Injection 7,8-Dihydro-7-alpha-(1-(R)-hydroxy-1-methylbutyl)-O(sup 6)-methyl-6,14-endo-ethenomorphine EINECS 238-535-9 SCHEMBL20507 11022-38-1 6,14-ethenomorphinan-3-ol, 7,8-didehydro-4,5-epoxy-18,19-dihydro-18-[(1R)-1-hydroxy-1-methylbutyl]-6-methoxy-17-methyl-, (5alpha,6beta,14beta,18R)- AC1LD8RO Etorphine (except hydrochloride salt) HSDB 7601 UNII-42M2Y6NU9O 19478-25-2 6,14-Ethenomorphinan-7-methanol, 4,5-epoxy-3-hydroxy-6-methoxy-alpha,17-dimethyl-alpha-propyl-, (alphaR,5alpha,7alpha)- (9CI) CHEMBL140050 Oripavine, 6,14-endo-ethylenetetrahydro-7-(1-hydroxy-1-methylbutyl)- (7CI) 6,14-endo-Ethenotetrahydrooripavine, 7-alpha-(1-hydroxy-1-methylbutyl)- 7-alpha-(1-(R)-Hydroxy-1-methylbutyl)-6,14-endo-ethenotetrahydrooripavine Etorfina [DCIT] [ Show all ]
Inchi Key	CAHCBJPUTCKATP-FAWZKKEFSA-N
Inchi ID	InChI=1S/C25H33NO4/c1-5-8-22(2,28)17-14-23-9-10-25(17,29-4)21-24(23)11-12-26(3)18(23)13-15-6-7-16(27)20(30-21)19(15)24/h6-7,9-10,17-18,21,27-28H,5,8,11-14H2,1-4H3/t17-,18-,21-,22-,23-,24+,25-/m1/s1
PubChem CID	644209
ChEMBL	CHEMBL140050
IUPHAR	N/A
BindingDB	50123599
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
37158	Delta-type opioid receptor	P33533	Oprd1	Rattus norvegicus (Rat)	372
37161	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
37165	Delta-type opioid receptor	P32300	Oprd1	Mus musculus (Mouse)	372
37159	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
37162	Kappa-type opioid receptor	P41144	OPRK1	Cavia porcellus (Guinea pig)	380
37164	Kappa-type opioid receptor	P34975	Oprk1	Rattus norvegicus (Rat)	380
37160	Mu-type opioid receptor	P33535	Oprm1	Rattus norvegicus (Rat)	398
37163	Mu-type opioid receptor	P97266	OPRM1	Cavia porcellus (Guinea pig)	98

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