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GPCR

NameNeuropeptide FF receptor 1
SpeciesHomo sapiens (Human)
GeneNPFFR1
SynonymGnIH-R
G protein-coupled receptor 147
OT7T022
NPFF1R1
NPFF1 receptor
[ Show all ]
DiseaseN/A
Length430
Amino acid sequenceMEGEPSQPPNSSWPLSQNGTNTEATPATNLTFSSYYQHTSPVAAMFIVAYALIFLLCMVGNTLVCFIVLKNRHMHTVTNMFILNLAVSDLLVGIFCMPTTLVDNLITGWPFDNATCKMSGLVQGMSVSASVFTLVAIAVERFRCIVHPFREKLTLRKALVTIAVIWALALLIMCPSAVTLTVTREEHHFMVDARNRSYPLYSCWEAWPEKGMRRVYTTVLFSHIYLAPLALIVVMYARIARKLCQAPGPAPGGEEAADPRASRRRARVVHMLVMVALFFTLSWLPLWALLLLIDYGQLSAPQLHLVTVYAFPFAHWLAFFNSSANPIIYGYFNENFRRGFQAAFRARLCPRPSGSHKEAYSERPGGLLHRRVFVVVRPSDSGLPSESGPSSGAPRPGRLPLRNGRVAHHGLPREGPGCSHLPLTIPAWDI
UniProtQ9GZQ6
Protein Data BankN/A
GPCR-HGmod modelQ9GZQ6
3D structure modelThis predicted structure model is from GPCR-EXP Q9GZQ6.
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL5951
IUPHAR300
DrugBankN/A

Known ligands

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Total entries: 141
Page:  / 2 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
4417562D structureCHEMBL3361427C22H36N6O400.5714 / 42.7Yes
4418372D structureCHEMBL3361419C24H34N6O3454.5756 / 41.7Yes
4419162D structureCHEMBL3361412C35H52N6O5636.8388 / 46.5No
4420502D structureCHEMBL3360831C19H33N7O375.5215 / 5-0.1Yes
168972D structureCHEMBL574565C13H11F3N4O296.2536 / 22.4Yes
168992D structureCID 69536911C13H11F3N4O296.2536 / 22.4Yes
173112D structureCHEMBL2208340C22H28N6O3424.5054 / 50.5Yes
173132D structureCHEMBL2204019C22H28N6O3424.5054 / 50.5Yes
173152D structureCHEMBL2208339C22H28N6O3424.5054 / 50.5Yes
214242D structureCHEMBL572825C15H18N4O270.3363 / 22.7Yes
4425462D structureCHEMBL3361418C26H32N6O444.5834 / 43.0Yes
245212D structureCHEMBL2208309C19H28N6O5420.476 / 6-1.7No
4427902D structureCHEMBL3361420C23H32N6O2424.5495 / 41.7Yes
4430462D structureCHEMBL3422010C21H19N5OS2421.5376 / 03.0Yes
353182D structureCHEMBL2208074C23H30N6O4454.5315 / 60.3No
4431602D structureCHEMBL3422516C89H128N20O181766.1221 / 216.5No
4432432D structureCHEMBL3422407C65H85N17O161360.517 / 20-1.9No
402302D structureCHEMBL2208297C30H33N7O3539.644 / 62.8No
468492D structureCHEMBL573738C13H14N4O242.2823 / 21.9Yes
493712D structureCHEMBL388586C41H51FN10O6798.9218 / 92.4No
580672D structureCHEMBL2208295C26H30N6O3474.5654 / 51.9Yes
4440712D structureCHEMBL3422018C20H18N6OS2422.5257 / 02.8Yes
5233752D structureCHEMBL508974C32H38N6O6602.6927 / 63.4No
637022D structureCHEMBL2208311C25H29N7O3475.5535 / 51.0Yes
4443532D structureCHEMBL3361414C37H48N6O5656.8288 / 47.5No
4446522D structureCHEMBL3361429C26H32N6O444.5834 / 43.0Yes
745822D structureCHEMBL2208076C24H30N6O4466.5425 / 60.8No
760252D structureCHEMBL2208070C25H34N6O5498.5846 / 50.6Yes
4455062D structureCHEMBL3360836C20H27N5337.4713 / 32.3Yes
971802D structureCHEMBL2208075C23H30N6O5470.536 / 7-0.1No
4456322D structureCHEMBL3352907C34H50N6O5622.8118 / 46.1No
1112852D structureCHEMBL2208333C23H30N6O4454.5315 / 50.7Yes
1166792D structureCHEMBL2208308C21H33N7O3431.5415 / 6-1.1No
1171092D structureCHEMBL573519C14H14F3N5309.2965 / 22.1Yes
1179832D structureCHEMBL2208312C25H29N7O3475.5535 / 51.3Yes
1222952D structureCHEMBL2208080C26H36N6O3480.6134 / 52.4Yes
1375962D structureCHEMBL2208314C23H28N8O3464.535 / 60.6No
4471582D structureCHEMBL3422408C66H85N19O151384.5218 / 19-1.6No
4472492D structureCHEMBL3361424C24H33N5O407.5623 / 32.6Yes
1416842D structureCHEMBL2208078C29H32N6O4528.6135 / 52.0No
4475882D structureCHEMBL3361436C29H35N5O469.6333 / 33.9Yes
1500452D structure311309-27-0C45H72N14O10969.15912 / 11-2.5No
1517182D structureCHEMBL2208331C22H26Cl2N6O3493.3894 / 51.9Yes
4477502D structureCHEMBL3361434C23H29Cl2N5O462.4193 / 33.5Yes
4478662D structureCHEMBL3361416C22H30N6O394.5234 / 41.8Yes
4478792D structureCHEMBL3361421C22H28Cl2N6O463.4074 / 43.0Yes
1576892D structureCHEMBL2165922C12H20N4220.322 / 21.4Yes
4480002D structureCHEMBL3361423C23H31N5O393.5353 / 32.3Yes
1615172D structureCHEMBL2208059C24H30N6O4466.5425 / 60.8No
1645102D structureCHEMBL2208073C23H30N6O4454.5315 / 60.3No
1707392D structureCHEMBL2208328C21H27N7O3425.4935 / 5-0.6Yes
4487212D structureCHEMBL3361417C23H32N6O408.554 / 41.2Yes
4487462D structureCHEMBL3360834C29H39N7O501.6795 / 52.7No
1788612D structureBIBP3226C27H31N5O3473.5774 / 52.5Yes
4487622D structureCHEMBL3361435C27H33N5O443.5953 / 33.5Yes
1833172D structureCHEMBL2208081C22H29N7O4455.5196 / 5-0.1Yes
4489632D structureCHEMBL3361415C38H50N6O5670.8558 / 47.4No
1927712D structureCHEMBL2208316C23H30N6O3438.5324 / 50.4Yes
1927722D structureSCHEMBL7535795C23H30N6O3438.5324 / 50.4Yes
1927752D structureCHEMBL2208317C23H30N6O3438.5324 / 50.4Yes
1983842D structureCHEMBL2208301C30H35N7O3S573.7166 / 52.5No
1992222D structureCHEMBL2208327C21H27N7O3425.4935 / 5-0.4Yes
4497132D structureCHEMBL3361413C37H48N6O5656.8288 / 47.5No
2085062D structureCHEMBL573518C13H11F3N4S312.3146 / 23.0Yes
2231842D structureCHEMBL1672379C40H64N12O11889.02513 / 12-5.0No
2279352D structureCHEMBL2208067C24H32N6O3452.5594 / 50.8Yes
2375592D structureSCHEMBL7560327C24H29N7O3463.5424 / 61.1No
2443112D structureCHEMBL2208320C28H32N6O3500.6034 / 52.3No
2443142D structureCHEMBL2208338C28H32N6O3500.6034 / 52.3No
2443152D structureCHEMBL2208337C28H32N6O3500.6034 / 52.3No
4513562D structureCHEMBL3361410C23H32N6O408.554 / 41.5Yes
2490902D structureSCHEMBL7528463C22H27ClN6O3458.9474 / 51.3Yes
2525362D structurePeptide analogue, 19C42H52FN9O5781.9347 / 83.4No
2561972D structureCHEMBL2208065C26H44N6O3488.6774 / 53.4Yes
2577692D structureCHEMBL2208062C23H29N7O3451.5315 / 50.0Yes
2650812D structureCHEMBL2208323C28H32N6O3500.6034 / 52.3No
2650822D structureCHEMBL2208322C28H32N6O3500.6034 / 52.3No
2650842D structureCHEMBL2208321C28H32N6O3500.6034 / 52.3No
4524802D structureCHEMBL3361428C23H32N6O408.554 / 42.2Yes
2777832D structureCHEMBL2208298C23H28N8O3464.535 / 60.2No
2786212D structureCHEMBL2208299C29H34N6O3514.634 / 52.3No
2786242D structureCHEMBL2208319C29H34N6O3514.634 / 52.3No
2786262D structureCHEMBL2208318C29H34N6O3514.634 / 52.3No
2793342D structureCHEMBL572531C8H8Cl2N4231.082 / 21.9Yes
2875822D structureCHEMBL2208332C22H26Cl2N6O3493.3894 / 51.9Yes
4531422D structureCHEMBL3361426C15H24N6O304.3984 / 5-0.2Yes
4531562D structureCHEMBL3361431C22H29BrN6O473.4194 / 42.5Yes
2943462D structureCHEMBL2208304C24H30N6O3450.5434 / 51.1Yes
2943482D structureCHEMBL2208303C24H30N6O3450.5434 / 51.1Yes
2943512D structureCHEMBL2208302C24H30N6O3450.5434 / 51.1Yes
2947712D structureCHEMBL2208066C20H32N6O3404.5154 / 50.2Yes
2950172D structureCHEMBL2208326C28H32N6O3500.6034 / 52.3No
2950182D structureCHEMBL2208325C28H32N6O3500.6034 / 52.3No
2950202D structureCHEMBL2208324C28H32N6O3500.6034 / 52.3No
4534132D structureCHEMBL3361433C27H33N5O443.5953 / 33.5Yes
2971992D structureKisspeptin-10C63H83N17O141302.4616 / 18-1.9No
4539782D structureCHEMBL3360833C26H39N7O465.6465 / 51.9Yes
4540402D structureCHEMBL3361425C22H30N6O394.5234 / 41.6Yes
3160962D structureCHEMBL2208068C24H32N6O4468.5585 / 50.6Yes
5306032D structureCHEMBL3746851C34H38F3N9O6725.7312 / 7N/ANo

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