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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	311309-27-0
Molecular formula	C45H72N14O10
IUPAC name	(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-4-amino-2-[[(2S)-1-[(2S)-2-amino-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]-4-oxobutanoyl]amino]-4-methylpentanoyl]pyrrolidine-2-carbonyl]amino]-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pentanediamide
Molecular weight	969.159
Hydrogen bond acceptor	12
Hydrogen bond donor	11
XlogP	-2.5
Synonyms	ZINC169289418 Neuropeptide NPVF BDBM50029188 RFRP 3 (human) CHEMBL2165920 Neuropeptide VF (124-131) (human) BDBM86143 RFRP-3 L-Val-L-Pro-L-Asn-L-Leu-L-Pro-L-Gln-L-Arg-L-Phe-NH2 AKOS024458292 RFamide-related peptide 3 [ Show all ]
Inchi Key	JFZCLMZUABKABL-GVCDGELBSA-N
Inchi ID	InChI=1S/C45H72N14O10/c1-24(2)21-31(57-40(65)30(23-35(47)61)56-42(67)33-15-10-20-59(33)44(69)36(48)25(3)4)43(68)58-19-9-14-32(58)41(66)54-28(16-17-34(46)60)39(64)53-27(13-8-18-52-45(50)51)38(63)55-29(37(49)62)22-26-11-6-5-7-12-26/h5-7,11-12,24-25,27-33,36H,8-10,13-23,48H2,1-4H3,(H2,46,60)(H2,47,61)(H2,49,62)(H,53,64)(H,54,66)(H,55,63)(H,56,67)(H,57,65)(H4,50,51,52)/t27-,28-,29-,30-,31-,32-,33-,36-/m0/s1
PubChem CID	71451611
ChEMBL	CHEMBL2165920
IUPHAR	N/A
BindingDB	50029188, 86143
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
150045	Neuropeptide FF receptor 1	Q9GZQ6	NPFFR1	Homo sapiens (Human)	430
150043	Neuropeptide FF receptor 2	Q9Y5X5	NPFFR2	Homo sapiens (Human)	522
150044	Neuropeptide FF receptor 2	Q9EQD2	Npffr2	Rattus norvegicus (Rat)	417
556049	Prolactin-releasing peptide receptor	P49683	PRLHR	Homo sapiens (Human)	370

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