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Name | Prolactin-releasing peptide receptor |
---|---|
Species | Homo sapiens (Human) |
Gene | PRLHR |
Synonym | PrRP receptor hGR3 GPR10 G-protein coupled receptor 10 G protein-coupled receptor 10 [ Show all ] |
Disease | N/A |
Length | 370 |
Amino acid sequence | MASSTTRGPRVSDLFSGLPPAVTTPANQSAEASAGNGSVAGADAPAVTPFQSLQLVHQLKGLIVLLYSVVVVVGLVGNCLLVLVIARVRRLHNVTNFLIGNLALSDVLMCTACVPLTLAYAFEPRGWVFGGGLCHLVFFLQPVTVYVSVFTLTTIAVDRYVVLVHPLRRRISLRLSAYAVLAIWALSAVLALPAAVHTYHVELKPHDVRLCEEFWGSQERQRQLYAWGLLLVTYLLPLLVILLSYVRVSVKLRNRVVPGCVTQSQADWDRARRRRTFCLLVVIVVVFAVCWLPLHVFNLLRDLDPHAIDPYAFGLVQLLCHWLAMSSACYNPFIYAWLHDSFREELRKLLVAWPRKIAPHGQNMTVSVVI |
UniProt | P49683 |
Protein Data Bank | N/A |
GPCR-HGmod model | P49683 |
3D structure model | This predicted structure model is from GPCR-EXP P49683. |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL1681611 |
IUPHAR | 337 |
DrugBank | N/A |
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GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
521508 | SCHEMBL434942 | C28H26F3N5O4 | 553.542 | 9 / 1 | 3.6 | No |
557358 | BDBM195750 | C28H26F3N5O4 | 553.542 | 9 / 1 | 3.6 | No |
535979 | SCHEMBL433646 | C27H21F4N5O2 | 523.492 | 8 / 1 | 3.0 | No |
521923 | SCHEMBL448663 | C26H24ClF3N4O3 | 532.948 | 7 / 1 | 4.2 | No |
522006 | SCHEMBL448265 | C23H23F3N4O3S | 492.517 | 8 / 1 | 3.5 | Yes |
536443 | SCHEMBL437393 | C23H23F3N4O3S | 492.517 | 8 / 1 | 3.5 | Yes |
555586 | RFRP-1 | C64H96N18O12S | 1341.65 | 16 / 14 | 0.2 | No |
536761 | SCHEMBL437445 | C25H29FN4O3 | 452.53 | 6 / 0 | 3.8 | Yes |
522509 | SCHEMBL450759 | C23H29ClN4O3 | 444.96 | 4 / 1 | 3.8 | Yes |
536816 | SCHEMBL437468 | C23H29ClN4O3 | 444.96 | 4 / 1 | 3.8 | Yes |
536862 | SCHEMBL435858 | C28H24F3N5O2 | 519.528 | 7 / 1 | 3.4 | No |
536907 | SCHEMBL435078 | C28H28ClN5O3 | 518.014 | 5 / 1 | 4.3 | No |
522610 | SCHEMBL448529 | C28H28ClN5O3 | 518.014 | 5 / 1 | 4.3 | No |
519858 | CHEMBL3734024 | C22H20Cl2N4O3 | 459.327 | 4 / 1 | 3.1 | Yes |
522636 | SCHEMBL435811 | C25H24ClF3N4O4 | 536.936 | 8 / 1 | 3.8 | No |
536933 | CHEMBL3914667 | C25H24ClF3N4O4 | 536.936 | 8 / 1 | 3.8 | No |
522900 | SCHEMBL437451 | C26H25F3N4O3 | 498.506 | 7 / 1 | 3.9 | Yes |
537205 | SCHEMBL435946 | C28H29ClN6O3 | 533.029 | 5 / 1 | 3.6 | No |
522937 | SCHEMBL448660 | C28H29ClN6O3 | 533.029 | 5 / 1 | 3.6 | No |
49374 | CHEMBL388586 | C41H51FN10O6 | 798.921 | 8 / 9 | 2.4 | No |
519910 | CHEMBL3986697 | C25H26ClF3N6O3 | 550.967 | 9 / 1 | 4.1 | No |
523171 | SCHEMBL437427 | C25H26Cl2N4O3 | 501.408 | 4 / 1 | 4.5 | No |
523265 | SCHEMBL451382 | C26H28Cl2F3N5O3 | 586.437 | 8 / 2 | N/A | No |
523473 | SCHEMBL447186 | C28H25ClF3N5O2 | 555.986 | 7 / 2 | N/A | No |
523804 | CHEMBL3729141 | C28H25F3N6O2 | 534.543 | 7 / 2 | 3.5 | No |
523836 | CHEMBL3728776 | C26H25F3N4O3S | 530.566 | 8 / 1 | 3.5 | No |
524057 | SCHEMBL448475 | C26H25F3N6O3S | 558.58 | 9 / 1 | 3.1 | No |
538168 | SCHEMBL437465 | C26H25F3N6O3S | 558.58 | 9 / 1 | 3.1 | No |
524058 | CHEMBL3728036 | C28H23F4N5O2 | 537.519 | 8 / 1 | 3.5 | No |
524424 | SCHEMBL435913 | C28H27F3N4O3 | 524.544 | 7 / 1 | 3.7 | No |
524516 | SCHEMBL436170 | C25H22Cl2N4O2 | 481.377 | 3 / 1 | 3.6 | Yes |
520152 | CHEMBL3916965 | C27H26F3N5O2 | 509.533 | 7 / 1 | 4.1 | No |
524712 | CHEMBL3727401 | C24H23Cl2F3N4O3 | 543.368 | 7 / 2 | N/A | No |
524838 | SCHEMBL435818 | C26H24F3N5O3S | 543.565 | 9 / 1 | 4.1 | No |
560842 | BDBM195751 | C26H24F3N5O3S | 543.565 | 9 / 1 | 4.1 | No |
524895 | CHEMBL3730970 | C27H22ClF4N5O2 | 559.95 | 8 / 2 | N/A | No |
525055 | SCHEMBL448302 | C28H26ClF3N6O2 | 571.001 | 7 / 2 | N/A | No |
525153 | SCHEMBL452917 | C22H20ClF3N4O4 | 496.871 | 8 / 1 | 3.5 | Yes |
539102 | SCHEMBL437449 | C22H20ClF3N4O4 | 496.871 | 8 / 1 | 3.5 | Yes |
555978 | Neuropeptide FF | C54H76N14O10 | 1081.29 | 12 / 12 | -0.3 | No |
555979 | AC1NQ0SC | C54H76N14O10 | 1081.29 | 12 / 12 | -0.3 | No |
525202 | SCHEMBL435882 | C29H29F3N4O2 | 522.572 | 6 / 1 | 4.4 | No |
525254 | SCHEMBL452128 | C24H23Cl2N5O3S | 532.44 | 6 / 2 | N/A | No |
525272 | CHEMBL3728270 | C25H26Cl2F3N5O2 | 556.411 | 7 / 2 | N/A | No |
525297 | SCHEMBL447581 | C26H23F4N5O3 | 529.496 | 9 / 1 | 3.5 | No |
539289 | SCHEMBL437481 | C26H23F4N5O3 | 529.496 | 9 / 1 | 3.5 | No |
525586 | SCHEMBL437435 | C30H26F3N5O2 | 545.566 | 7 / 1 | 4.0 | No |
539614 | CHEMBL3734010 | C25H21F4N5O3 | 515.469 | 9 / 1 | 2.9 | No |
525649 | SCHEMBL452315 | C27H24F3N5O3 | 523.516 | 8 / 1 | 3.4 | No |
539631 | SCHEMBL437401 | C27H24F3N5O3 | 523.516 | 8 / 1 | 3.4 | No |
539674 | SCHEMBL434965 | C30H26F3N5O3 | 561.565 | 8 / 1 | 3.8 | No |
525739 | CHEMBL3729222 | C24H24Cl2N4O4 | 503.38 | 5 / 1 | 3.5 | No |
539722 | SCHEMBL434988 | C24H24Cl2N4O4 | 503.38 | 5 / 1 | 3.5 | No |
556049 | 311309-27-0 | C45H72N14O10 | 969.159 | 12 / 11 | -2.5 | No |
540051 | SCHEMBL435939 | C26H23F3N4O3S | 528.55 | 8 / 1 | 4.5 | No |
526033 | CHEMBL3728107 | C30H26F3N5O3 | 561.565 | 8 / 1 | 3.7 | No |
526316 | CHEMBL3731865 | C24H26Cl3N5O2 | 522.855 | 4 / 2 | N/A | No |
556174 | BDBM50368404 | C112H174N36O27 | 2456.85 | 33 / 41 | -3.6 | No |
526466 | SCHEMBL448830 | C26H25F3N4O5 | 530.504 | 9 / 1 | 2.8 | No |
540485 | SCHEMBL435906 | C26H25F3N4O5 | 530.504 | 9 / 1 | 2.8 | No |
556189 | CHEMBL44246 | C27H31N5O3 | 473.577 | 4 / 5 | 2.5 | Yes |
179485 | N-Isobutyl-2,4,8,10,12-tetradecapentaenamide | C18H27NO | 273.42 | 1 / 1 | 4.9 | Yes |
526613 | SCHEMBL447348 | C25H24ClF6N5O2 | 575.94 | 10 / 2 | N/A | No |
527047 | SCHEMBL437447 | C26H24ClF3N4O3 | 532.948 | 7 / 0 | 4.1 | No |
527222 | SCHEMBL448484 | C27H25F3N4O5 | 542.515 | 9 / 1 | 3.8 | No |
541126 | SCHEMBL435923 | C27H25F3N4O5 | 542.515 | 9 / 1 | 3.8 | No |
541131 | SCHEMBL437394 | C28H25F3N6O2 | 534.543 | 7 / 1 | 3.2 | No |
527236 | SCHEMBL452594 | C25H22F3N5O3S | 529.538 | 9 / 1 | 3.7 | No |
541134 | SCHEMBL436929 | C25H22F3N5O3S | 529.538 | 9 / 1 | 3.7 | No |
520496 | CHEMBL3734026 | C23H20ClF3N4O3 | 492.883 | 7 / 1 | 3.3 | Yes |
527441 | CHEMBL3732064 | C26H23Cl2F3N4O2 | 551.391 | 6 / 2 | N/A | No |
527644 | SCHEMBL452837 | C28H24F3N5O2 | 519.528 | 7 / 1 | 3.4 | No |
527702 | CHEMBL3731809 | C30H30F3N5O3 | 565.597 | 7 / 1 | 3.1 | No |
527740 | SCHEMBL448840 | C27H29ClN4O5 | 525.002 | 6 / 1 | 3.5 | No |
541665 | SCHEMBL437458 | C27H29ClN4O5 | 525.002 | 6 / 1 | 3.5 | No |
527800 | SCHEMBL450489 | C26H27F3N4O3 | 500.522 | 7 / 1 | 3.8 | No |
541751 | SCHEMBL437437 | C26H27F3N4O3 | 500.522 | 7 / 1 | 3.8 | No |
527841 | CHEMBL3728414 | C26H25ClF4N6O2 | 564.97 | 9 / 2 | N/A | No |
527874 | CHEMBL3727412 | C26H26ClF3N4O3 | 534.964 | 7 / 1 | 4.0 | No |
541803 | CHEMBL3901490 | C26H26ClF3N4O3 | 534.964 | 7 / 1 | 4.0 | No |
528134 | SCHEMBL437371 | C25H24ClF3N4O3S | 552.997 | 8 / 1 | 4.3 | No |
542029 | CHEMBL3969131 | C25H24ClF3N4O3S | 552.997 | 8 / 1 | 4.3 | No |
528197 | SCHEMBL448631 | C22H20ClF3N4O3S | 512.932 | 8 / 1 | 4.1 | No |
542132 | SCHEMBL436905 | C22H20ClF3N4O3S | 512.932 | 8 / 1 | 4.1 | No |
528298 | SCHEMBL435817 | C25H22F6N4O4 | 556.465 | 11 / 1 | 4.3 | No |
564710 | BDBM195746 | C25H22F6N4O4 | 556.465 | 11 / 1 | 4.3 | No |
528452 | SCHEMBL450105 | C26H21F5N4O2 | 516.472 | 8 / 1 | 3.4 | No |
528469 | SCHEMBL447217 | C28H28ClF3N6O3 | 589.016 | 9 / 2 | N/A | No |
556417 | PrRP24-31 | C42H67N13O9 | 898.08 | 11 / 10 | -1.8 | No |
542435 | SCHEMBL435830 | C24H22ClF3N4O3 | 506.91 | 7 / 1 | 3.7 | No |
528645 | SCHEMBL452039 | C23H21Cl2F3N4O3 | 529.341 | 7 / 2 | N/A | No |
252535 | Peptide analogue, 19 | C42H52FN9O5 | 781.934 | 7 / 8 | 3.4 | No |
528882 | SCHEMBL449454 | C24H25Cl3N4O3 | 523.839 | 4 / 2 | N/A | No |
529047 | SCHEMBL434947 | C26H24F3N5O3 | 511.505 | 8 / 1 | 3.2 | No |
565432 | BDBM195748 | C26H24F3N5O3 | 511.505 | 8 / 1 | 3.2 | No |
529257 | SCHEMBL448522 | C28H24ClF4N5O2 | 573.977 | 8 / 2 | N/A | No |
543361 | SCHEMBL434957 | C28H23F4N5O2 | 537.519 | 8 / 1 | 3.5 | No |
529447 | SCHEMBL450296 | C27H25Cl2F3N4O2 | 565.418 | 6 / 2 | N/A | No |
529474 | SCHEMBL450716 | C28H27ClF4N6O3 | 607.007 | 10 / 2 | N/A | No |
543585 | SCHEMBL435859 | C27H24ClF3N4O2 | 528.96 | 6 / 1 | 4.3 | No |
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