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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Neuropeptide FF receptor 1
Species	Homo sapiens (Human)
Gene	NPFFR1
Synonym	GnIH-R G protein-coupled receptor 147 OT7T022 NPFF1R1 NPFF1 receptor NPFF1 G-protein coupled receptor 147 GPR147 GnIH-R/RFRP-3 RFamide-related peptide receptor OT7T022 [ Show all ]
Disease	N/A
Length	430
Amino acid sequence	MEGEPSQPPNSSWPLSQNGTNTEATPATNLTFSSYYQHTSPVAAMFIVAYALIFLLCMVGNTLVCFIVLKNRHMHTVTNMFILNLAVSDLLVGIFCMPTTLVDNLITGWPFDNATCKMSGLVQGMSVSASVFTLVAIAVERFRCIVHPFREKLTLRKALVTIAVIWALALLIMCPSAVTLTVTREEHHFMVDARNRSYPLYSCWEAWPEKGMRRVYTTVLFSHIYLAPLALIVVMYARIARKLCQAPGPAPGGEEAADPRASRRRARVVHMLVMVALFFTLSWLPLWALLLLIDYGQLSAPQLHLVTVYAFPFAHWLAFFNSSANPIIYGYFNENFRRGFQAAFRARLCPRPSGSHKEAYSERPGGLLHRRVFVVVRPSDSGLPSESGPSSGAPRPGRLPLRNGRVAHHGLPREGPGCSHLPLTIPAWDI
UniProt	Q9GZQ6
Protein Data Bank	N/A
GPCR-HGmod model	Q9GZQ6
3D structure model	This predicted structure model is from GPCR-EXP Q9GZQ6.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5951
IUPHAR	300
DrugBank	N/A

Ligand

Name	CHEMBL3361421
Molecular formula	C22H28Cl2N6O
IUPAC name	N-[[1-benzyl-4-(3,4-dichloroanilino)piperidin-4-yl]methyl]-2-(diaminomethylideneamino)acetamide
Molecular weight	463.407
Hydrogen bond acceptor	4
Hydrogen bond donor	4
XlogP	3.0
Synonyms	BDBM50029120
Inchi Key	JPABNGMHNZSXOV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H28Cl2N6O/c23-18-7-6-17(12-19(18)24)29-22(15-28-20(31)13-27-21(25)26)8-10-30(11-9-22)14-16-4-2-1-3-5-16/h1-7,12,29H,8-11,13-15H2,(H,28,31)(H4,25,26,27)
PubChem CID	118724982
ChEMBL	CHEMBL3361421
IUPHAR	N/A
BindingDB	50029120
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	191.0 nM	PMID25268943	BindingDB,ChEMBL

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