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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
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Ligand

Name	Dextropropoxyphene
Molecular formula	C22H29NO2
IUPAC name	[(2S,3R)-4-(dimethylamino)-3-methyl-1,2-diphenylbutan-2-yl] propanoate
Molecular weight	339.479
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	4.2
Synonyms	S2F83W92TK 2-Butanol, 4-(dimethylamino)-3-methyl-1,2-diphenyl-, propionate (ester), (2S,3R)- [(2S,3R)-4-(dimethylamino)-3-methyl-1,2-diphenylbutan-2-yl] propanoate Abalgin (Salt/Mix) alpha-D-4-Dimethylamino-3-methyl-1,2-diphenyl-2-butanol-propionat [German] C07406 Darvon Dextropropoxifeno Dextropropoxyphene[INN:BAN] DTXSID1023524 Propoxypene (+)-Propoxyphene solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material (D)-PROPOXYPHENE UNII-II2G62OV6F component XLMALTXPSGQGBX-GCJKJVERSA-N 2621-61-6 alpha-(+)-4-Dimethylamino-1,2-diphenyl-3-methyl-2-butanol propionate ester Benzeneethanol, .alpha.-[2-(dimethylamino)-1-methylethyl]-.alpha.-phenyl-, propanoate (ester), [S-(R,S)]- CHEBI:51173 DB00647 Dextroproxifeno Femadol Propoxyphene-d .alpha.-d-Propoxyphene XLMALTXPSGQGBX-GCJKJVERSA-N 469-62-5 alpha-D-4-Dimethylamino-3-methyl-1,2-diphenyl-2-butanol propionate Benzeneethanol, alpha-(2-(dimethylamino)-1-methylethyl)-alpha-phenyl-, propanoate (ester), (S-(R,S))- D07809 Destropropossifene Dextropropoxyphene 1.0 mg/ml in Acetonitrile Doloxen (Salt/Mix) LS-46517 (+)-4-Dimethylamino-1,2-diphenyl-3-methyl-2-propionyloxybutane Proxyvon SCHEMBL25405 2-Butanol, 4-(dimethylamino)-3-methyl-1,2-diphenyl-, propionate, (+)- [(2S,3R)-4-dimethylamino-3-methyl-1,2-di(phenyl)butan-2-yl] propanoate AC1L1UHN Antalvic C22H29NO2 Darvon (Salt/Mix) Dextropropoxifeno [INN-Spanish] Dextropropoxyphenum EINECS 207-420-5 propoxyphene (1S,2R)-1-benzyl-3-(dimethylamino)-2-methyl-1-phenylpropyl propanoate (S)-alpha-(2-(Dimethylamino)-1-methylethyl)-alpha-phenylbenzeneethanol propanoate UNII-S2F83W92TK 3818-94-8 alpha-(+)-4-Dimethylamino-1,2-diphenyl-3-methyl-2-propionoxybutane Benzeneethanol, .alpha.-[2-(dimethylamino)-1-methylethyl]-.alpha.-phenyl-, propanoate, [S-(R,S)]- CHEMBL1213351 DEA No. 9273 Dextropropoxyphene (INN) Dextroproxifeno [Spanish] GTPL7593 (+)-1,2-Diphenyl-2-propionoxy-3-methyl-4-dimethylaminobutane Proxagesic Romidon (Salt/Mix) 1-Benzyl-3-(dimethylamino)-2-methyl-1-phenylpropyl propionate, [S-(R,S)]- # ZINC1530769 alpha-D-4-Dimethylamino-3-methyl-1,2-diphenyl-2-butanol-propionat Bulk dextropropoxyphene (non-dosage forms) D0D4PB Destropropossifene [DCIT] Dextropropoxyphene [INN:BAN] Doloxene (Salt/Mix) Methanol, compd. with (+-)-alpha-(2-dimethylamino)-1-methylethyl-alpha- phenylphenethyl propionate (1:1) (+)-alpha-propoxyphene SK 65 21086-94-2 Algafan BDBM82269 CAS_469-62-5 Dextropropoxyphen Dextropropoxyphenum [INN-Latin] Erantin (Salt/Mix) Propoxyphene, (+)- (2S,3R)-(+)-4-(Dimethylamino)-3-methyl-1,2-diphenyl-2-butanol propionate(ester) .alpha.-(+)-4-Dimethylamino-1,2-diphenyl-3-methyl-2-butanol propionate ester USAF EL-84 4-Dimethylamino-3-methyl-1,2-diphenyl-2-propoxybutane alpha-4-Dimethylamino-1,2-diphenyl-3-methyl-2-butanol propionate Benzeneethanol, alpha-((1R)-2-(dimethylamino)-1-methylethyl)-alpha-phenyl-, propanoate (ester), (alphaS)- d-Propoxyphene Depromic Dextropropoxyphene 0.1 mg/ml in Acetonitrile Dolene (Salt/Mix) HSDB 3175 (+)-4-(Dimethylamino)-3-methyl-1,2-diphenyl-2-butanol propionate Proxyphen [ Show all ]
Inchi Key	XLMALTXPSGQGBX-GCJKJVERSA-N
Inchi ID	InChI=1S/C22H29NO2/c1-5-21(24)25-22(18(2)17-23(3)4,20-14-10-7-11-15-20)16-19-12-8-6-9-13-19/h6-15,18H,5,16-17H2,1-4H3/t18-,22+/m1/s1
PubChem CID	10100
ChEMBL	N/A
IUPHAR	N/A
BindingDB	82269
DrugBank	DB00647
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
394991	Delta-type opioid receptor	P33533	Oprd1	Rattus norvegicus (Rat)	372
552748	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
394992	Kappa-type opioid receptor	P34975	Oprk1	Rattus norvegicus (Rat)	380
552747	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
532656	Mas-related G-protein coupled receptor member X2	Q96LB1	MRGPRX2	Homo sapiens (Human)	330
394993	Mu-type opioid receptor	P33535	Oprm1	Rattus norvegicus (Rat)	398
552746	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400

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