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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2376801
Molecular formula	C14H20N6
IUPAC name	7-ethyl-4-[(3R)-3-(methylamino)pyrrolidin-1-yl]pyrido[3,2-d]pyrimidin-2-amine
Molecular weight	272.356
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	1.2
Synonyms	BDBM50433356 SCHEMBL14895496
Inchi Key	QEDDBMMRWNQKSG-SNVBAGLBSA-N
Inchi ID	InChI=1S/C14H20N6/c1-3-9-6-11-12(17-7-9)13(19-14(15)18-11)20-5-4-10(8-20)16-2/h6-7,10,16H,3-5,8H2,1-2H3,(H2,15,18,19)/t10-/m1/s1
PubChem CID	71525679
ChEMBL	CHEMBL2376801
IUPHAR	N/A
BindingDB	50433356
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
276028	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487
276027	Histamine H2 receptor	P25021	HRH2	Homo sapiens (Human)	359
276030	Histamine H3 receptor	Q9Y5N1	HRH3	Homo sapiens (Human)	445
276029	Histamine H4 receptor	Q9H3N8	HRH4	Homo sapiens (Human)	390
276031	Histamine H4 receptor	Q91ZY2	Hrh4	Mus musculus (Mouse)	391
276032	Histamine H4 receptor	Q91ZY1	Hrh4	Rattus norvegicus (Rat)	391

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