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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3805361
Molecular formula	C19H24N6S
IUPAC name	1-cyano-2-[[(1S,3S)-3-(1H-imidazol-5-yl)cyclopentyl]methyl]-3-(2-phenylsulfanylethyl)guanidine
Molecular weight	368.503
Hydrogen bond acceptor	4
Hydrogen bond donor	3
XlogP	2.8
Synonyms	BDBM50170126 J3.639.707A 1-[[(1S,3S)-3-(1H-Imidazole-4-yl)cyclopentane-1-yl]methyl]-2-cyano-3-[2-(phenylthio)ethyl]guanidine
Inchi Key	MMZLYDNVAYWZLR-HOTGVXAUSA-N
Inchi ID	InChI=1S/C19H24N6S/c20-13-24-19(22-8-9-26-17-4-2-1-3-5-17)23-11-15-6-7-16(10-15)18-12-21-14-25-18/h1-5,12,14-16H,6-11H2,(H,21,25)(H2,22,23,24)/t15-,16-/m0/s1
PubChem CID	127052293
ChEMBL	CHEMBL3805361
IUPHAR	N/A
BindingDB	50170126
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
527514	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487
527518	Histamine H2 receptor	P25021	HRH2	Homo sapiens (Human)	359
527515	Histamine H3 receptor	Q9Y5N1	HRH3	Homo sapiens (Human)	445
527516	Histamine H4 receptor	Q91ZY2	Hrh4	Mus musculus (Mouse)	391
527517	Histamine H4 receptor	Q9H3N8	HRH4	Homo sapiens (Human)	390

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