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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	VUF-2274
Molecular formula	C28H29ClN2O
IUPAC name	5-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-2,2-diphenylpentanenitrile
Molecular weight	445.003
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	5.6
Synonyms	5-(4-(4-chlorophenyl)-4-hydroxy-piperidin-1-yl)-2,2-diphenylpentanenitrile 5-[4-(4-chlorophenyl)-4-hydroxy-1-piperidyl]-2,2-diphenyl-pentanenitrile NCGC00378719-01 AKOS024256779 ZINC3991118 5-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-2,2-diphenylpentanenitrile CHEMBL34166 SCHEMBL8891715 1-Piperidinepentanenitrile, 4-(4-chlorophenyl)-4-hydroxy-a,a-diphenyl- BDBM50027216 5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentanenitrile L000124 A1-01967 [ Show all ]
Inchi Key	MEEJEEVTIVAOJP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H29ClN2O/c29-26-14-12-25(13-15-26)28(32)17-20-31(21-18-28)19-7-16-27(22-30,23-8-3-1-4-9-23)24-10-5-2-6-11-24/h1-6,8-15,32H,7,16-21H2
PubChem CID	9889700
ChEMBL	CHEMBL34166
IUPHAR	N/A
BindingDB	50027216
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
203316	C-C chemokine receptor type 1	P32246	CCR1	Homo sapiens (Human)	355
203318	C-C chemokine receptor type 1	P51675	Ccr1	Mus musculus (Mouse)	355
203317	C-C chemokine receptor type 3	P51677	CCR3	Homo sapiens (Human)	355
203315	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
203314	G-protein coupled receptor homolog US28	P69332	US28	Human cytomegalovirus (strain AD169) (HHV-5)	354

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