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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	1-Benzyl-APDC
Molecular formula	C13H16N2O4
IUPAC name	(2R,4R)-4-amino-1-benzylpyrrolidine-2,4-dicarboxylic acid
Molecular weight	264.281
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	-4.5
Synonyms	4-amino-1-(phenylmethyl)pyrrolidine-2,4-dicarboxylic acid D0N0NJ FT-0772028 (2R,4R)-4-Amino-1-benzyl-pyrrolidine-2,4-dicarboxylic acid AJ-101168 ZINC39952128 171336-76-8 CHEMBL60238 (2R)-1-Benzyl-4-aminopyrrolidine-2beta,4alpha-dicarboxylic acid 4-Amino-1-benzyl-pyrrolidine-2,4-dicarboxylic acid(1-benzyl-APDC) DB-064818 GTPL1436 (2R,4R)-4-amino-1-benzylpyrrolidine-2,4-dicarboxylic acid BDBM50071161 2,4-Pyrrolidinedicarboxylic acid, 4-amino-1-(phenylmethyl)-, (2R,4R)- CTK0A8043 (2R,4R)-1-BENZYL-4-AMINO-PYRROLIDINE-2,4-DIcarboxylic acid DTXSID60573467 SCHEMBL8061968 [ Show all ]
Inchi Key	LYCSUAGKQMUTBR-ZWNOBZJWSA-N
Inchi ID	InChI=1S/C13H16N2O4/c14-13(12(18)19)6-10(11(16)17)15(8-13)7-9-4-2-1-3-5-9/h1-5,10H,6-8,14H2,(H,16,17)(H,18,19)/t10-,13-/m1/s1
PubChem CID	15508178
ChEMBL	CHEMBL60238
IUPHAR	N/A
BindingDB	50071161
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
199214	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
199217	Metabotropic glutamate receptor 1	P23385	Grm1	Rattus norvegicus (Rat)	1199
199212	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
199215	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
199216	Metabotropic glutamate receptor 3	Q14832	GRM3	Homo sapiens (Human)	879
199218	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
199213	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203
199220	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
199219	Metabotropic glutamate receptor 6	O15303	GRM6	Homo sapiens (Human)	877
199221	Metabotropic glutamate receptor 6	P35349	Grm6	Rattus norvegicus (Rat)	871
199211	Metabotropic glutamate receptor 8	O00222	GRM8	Homo sapiens (Human)	908

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