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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
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Ligand

Name	acebutolol
Molecular formula	C18H28N2O4
IUPAC name	N-[3-acetyl-4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]butanamide
Molecular weight	336.432
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	1.7
Synonyms	LS-45389 3'-(Acetyl-4'-(2-hydroxy-3-(isopropylamino)propoxy)butyranilide N-(3-acetyl-4-{2-hydroxy-3-[(propan-2-yl)amino]propoxy}phenyl)butanamide AB00053574_13 Neptal Acebutololo RP 21823 API0000343 SPBio_002178 BSPBio_001986 Wesfalin (Salt/Mix) C06803 D0HD9K Epitope ID:146105 KBio2_000971 (.+/-.)-3'-Acetyl-4'-[2-hydroxy-3-(isopropylamino)propoxy]butyranilide 1-(2-Acetyl-4-n-butyramidophenoxy)-2-hydroxy-3-isopropylaminopropane MCULE-6278379694 34381-68-5 (hydrochloride) N-[3-acetyl-4-[2-hydroxy-3-(isopropylamino)propoxy]phenyl]butanamide Acebrutololum Prent (TN) Acetobutolol SCHEMBL3772 BPBio1_000283 Spectrum4_000802 Butanamide, N-(3-acetyl-4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)phenyl)-,monohydrochloride,(+-)- CCRIS 9214 DivK1c_000612 GTPL7107 (+-)-3'-Acetyl-4'-(2-hydroxy-3-(isopropylamino)propoxy)butyranilide KBio3_001486 KS-000024QQ N-(3-Acetyl-4-[2-hydroxy-3-(isopropylamino)propoxy]phenyl)butanamide 5'-Butyramido-2'-(2-hydroxy-3-isopropylaminopropoxy)acetophenone N-{3-acetyl-4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl}butanamide Acebutolol (USAN/INN) Prestwick2_000069 AKOS015963037 Sectral (TN) BRN 2162244 ST2407367 Butanamide,N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]- CHEMBL642 DTXSID2048539 KB-258149 (+/-)-acebutolol (.+/-.)-Acebutolol M & B 17803A 3'-Acetyl-4'-(2-hydroxy-3-(isopropylamino)propoxy)butyranilide N-(3-acetyl-4-{2-hydroxy-3-[(propan-2-yl)amino]propoxy}phenyl)butanimidic acid AB00053574_14 NINDS_000612 Acebutololum SBI-0051584.P003 AX8112020 Spectrum2_001340 Butanamide, N-(3-acetyl-4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)phenyl)-, (+-)- C18H28N2O4 FT-0660953 KBio2_003539 1-[2-Acetyl-4-(butyrylamino)phenoxy]-3-(isopropylamino)-2-propanol MolPort-003-844-375 37517-30-9 N-[3-acetyl-4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]butanamide Acebrutololum [INN-Latin] Prestwick0_000069 Acetobutolol [INN-Spanish] Sectral BRD-A29260609-003-05-4 Spectrum5_001399 Butanamide, N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]- CHEBI:2379 dl-Acebutolol IDI1_000612 (+-)-Acebutolol KBioGR_001283 L000998 28197-63-9 N-(3-Acetyl-4-[2-hydroxy-3-(isopropylamino)propoxy]phenyl)butanamide # AB00053574 NCGC00018215-02 Acebutolol [USAN:INN:BAN] Prestwick3_000069 AN-25625 SPBio_001499 BSPBio_000257 ST2407368 C-34995 D02338 EINECS 253-539-0 KBio1_000612 (.+/-.)-3'-Acetyl-4'-[2-hydroxy-3-(1-methylethylamino)propoxy]butyranilide (.+/-.)-N-(3-Acetyl-4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)phenyl)butanamide M&B-17803 A 3'-Acetyl-4'-(2-hydroxy-3-isopropylaminopropoxy)butyranilid N-[3-Acetyl-4-(2-hydroxy-3-propan-2-ylaminopropoxy)-phenyl] butanamide AC1L1CNH Prent Acebutololum [INN-Latin] SC-47252 BDBM25755 Spectrum3_000573 Butanamide, N-(3-acetyl-4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)phenyl)-,monohydrochloride,( -)- CC-31988 DB01193 GOEMGAFJFRBGGG-UHFFFAOYSA-N KBio2_006107 KBioSS_000971 197A639 N-(3-Acetyl-4-(2-hydroxy-3-(isopropylamino)propoxy)phenyl)butyramide 4CH-016896 N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]butanamide Prestwick1_000069 ACM37517309 Sectral (Salt/Mix) BRD-A29260609-003-15-3 Spectrum_000491 Butanamide, N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]-, (.+/-.)- DS-3129 IL 17803A (Salt/Mix) (+-)-N-(3-Acetyl-4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)phenyl)butanamide [ Show all ]
Inchi Key	GOEMGAFJFRBGGG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H28N2O4/c1-5-6-18(23)20-14-7-8-17(16(9-14)13(4)21)24-11-15(22)10-19-12(2)3/h7-9,12,15,19,22H,5-6,10-11H2,1-4H3,(H,20,23)
PubChem CID	1978
ChEMBL	CHEMBL642
IUPHAR	N/A
BindingDB	25755
DrugBank	DB01193
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
101136	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
101134	Beta-1 adrenergic receptor	P08588	ADRB1	Homo sapiens (Human)	477
101137	Beta-1 adrenergic receptor	P18090	Adrb1	Rattus norvegicus (Rat)	466
101135	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
460121	Beta-2 adrenergic receptor	P10608	Adrb2	Rattus norvegicus (Rat)	418
101133	Beta-3 adrenergic receptor	P13945	ADRB3	Homo sapiens (Human)	408

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