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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2
Molecular formula	C51H71N13O11S2
IUPAC name	(2R)-N-[(2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl]-2-[[(2S,3R)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2R)-2-[[(2R)-2-amino-3-phenylpropanoyl]amino]-3-sulfanylpropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-hydroxybutanoyl]amino]-3-methyl-3-sulfanylbutanamide
Molecular weight	1106.33
Hydrogen bond acceptor	15
Hydrogen bond donor	17
XlogP	-0.6
Synonyms	BDBM85334 H-D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH(2) D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH(2) H-D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2
Inchi Key	GLWPFSWTTGSQRY-FGHAYEPSSA-N
Inchi ID	InChI=1S/C51H71N13O11S2/c1-26(65)39(42(53)68)62-49(75)41(51(3,4)77)64-48(74)40(27(2)66)63-44(70)35(15-10-20-56-50(54)55)58-46(72)37(23-30-24-57-34-14-9-8-13-32(30)34)60-45(71)36(22-29-16-18-31(67)19-17-29)59-47(73)38(25-76)61-43(69)33(52)21-28-11-6-5-7-12-28/h5-9,11-14,16-19,24,26-27,33,35-41,57,65-67,76-77H,10,15,20-23,25,52H2,1-4H3,(H2,53,68)(H,58,72)(H,59,73)(H,60,71)(H,61,69)(H,62,75)(H,63,70)(H,64,74)(H4,54,55,56)/t26-,27-,33-,35+,36+,37-,38+,39+,40+,41-/m1/s1
PubChem CID	11804285
ChEMBL	N/A
IUPHAR	N/A
BindingDB	85334
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
99637	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
460110	Delta-type opioid receptor	P79291	OPRD1	Sus scrofa (Pig)	228
99634	Kappa-type opioid receptor	P41144	OPRK1	Cavia porcellus (Guinea pig)	380
99636	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
99635	Mu-type opioid receptor	P97266	OPRM1	Cavia porcellus (Guinea pig)	98
555843	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400

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