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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL287587
Molecular formula	C8H10FNO3
IUPAC name	4-(2-amino-1-hydroxyethyl)-3-fluorobenzene-1,2-diol
Molecular weight	187.17
Hydrogen bond acceptor	5
Hydrogen bond donor	4
XlogP	-0.5
Synonyms	AC1L59C1 3-Fluoro-4-(1-hydroxy-2-aminoethyl)pyrocatechol 4-(2-Amino-1-hydroxy-ethyl)-3-fluoro-benzene-1,2-diol(2-FNE) (+/-)4-(2-Amino-1-hydroxy-ethyl)-3-fluoro-benzene-1,2-diol 1,2-Benzenediol, 4-(2-amino-1-hydroxyethyl)-3-fluoro-, (+-)- 3-Fluoronorepinephrine BDBM50019060 4-(2-Amino-1-hydroxyethyl)-3-fluoro-1,2-benzenediol # 71144-40-6 2-Fluoronorepinephrine 4-(2-Amino-1-hydroxy-ethyl)-3-fluoro-benzene-1,2-diol Benzenethanamine, 2-fluoro-.beta.,3,4-trihydroxy- 4-(2-amino-1-hydroxyethyl)-3-fluorobenzene-1,2-diol FOTRTWXNJQSQJS-UHFFFAOYSA-N 1,2-Benzenediol, 4-(2-amino-1-hydroxyethyl)-3-fluoro- [ Show all ]
Inchi Key	FOTRTWXNJQSQJS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C8H10FNO3/c9-7-4(6(12)3-10)1-2-5(11)8(7)13/h1-2,6,11-13H,3,10H2
PubChem CID	172745
ChEMBL	CHEMBL287587
IUPHAR	N/A
BindingDB	50019060
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
83605	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
83603	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
83601	Beta-1 adrenergic receptor	P18090	Adrb1	Rattus norvegicus (Rat)	466
83600	Beta-2 adrenergic receptor	P10608	Adrb2	Rattus norvegicus (Rat)	418
83602	Beta-2 adrenergic receptor	P54833	ADRB2	Canis lupus familiaris (Dog)	415
83604	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413

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