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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL212912
Molecular formula	C25H23Cl2N5O
IUPAC name	2-chloro-N-[3-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzodiazepin-11-yl]benzamide
Molecular weight	480.393
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	5.0
Synonyms	BDBM50190049 2-chloro-N-[8-chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,e][1,4]diazepin-5-yl]-benzamide
Inchi Key	DDNAXKKEJCCHMD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H23Cl2N5O/c1-30-12-14-31(15-13-30)24-19-7-3-5-9-22(19)32(23-11-10-17(26)16-21(23)28-24)29-25(33)18-6-2-4-8-20(18)27/h2-11,16H,12-15H2,1H3,(H,29,33)
PubChem CID	16007117
ChEMBL	CHEMBL212912
IUPHAR	N/A
BindingDB	50190049
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
57215	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
57211	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
57213	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
57214	D(1B) dopamine receptor	P21918	DRD5	Homo sapiens (Human)	477
57212	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
57216	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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