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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Medetomidine
Molecular formula	C13H16N2
IUPAC name	5-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
Molecular weight	200.285
Hydrogen bond acceptor	1
Hydrogen bond donor	1
XlogP	3.1
Synonyms	W-6033 (+-)-4-(alpha,2,3-trimethylbenzyl)imidazole 4-(1-(2,3-Dimethylphenyl)ethyl)-1H-imidazole AC1L2A2Y BDBM50036913 D08165 IH-Imidazole, 4(1-(2,3-dimethylphenyl)ethyl)- Medetomidine (INN) (S)-medetomidine; Dexmedetomidinum 5-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole API0008707 DoMtor L001361 Medetomidinum [Latin] ( -)-4-(alpha,2,3-Trimethylbenzyl)imidazole 1H-Imidazole, 4-[1-(2,3-dimethylphenyl)ethyl]- 86347-15-1 (hydrochloride) BCP06913 CTK6C1550 HMS3651H20 Medetomidina [Spanish] SC-94517 (RS)-4-(alpha,2,3-Trimethylbenzyl)imidazol 4-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole AK115836 BRD-A66563878-003-01-8 D0F2ML KS-00000GIZ Medetomidine [INN:BAN] AS-35172 CHEMBL77921 DTXSID6048258 LS-177922 MolPort-006-394-853 SCHEMBL26432 (+)-4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole 3506AC AB01566810_01 BCP12592 CUHVIMMYOGQXCV-UHFFFAOYSA-N HY-17034 (rs)-4-[1-(2,3-dimethylphenyl)ethyl]-3h-imidazole 5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole AKOS016010776 CHEBI:48552 Domitor [veterinary] (TN) L000223 Medetomidinum 1H-Imidazole, 4-(1-(2,3-dimethylphenyl)ethyl)- 86347-14-0 AX8137326 CS-0734 FT-0716677 Medetomidina MPV-785 [ Show all ]
Inchi Key	CUHVIMMYOGQXCV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)
PubChem CID	68602
ChEMBL	CHEMBL77921
IUPHAR	N/A
BindingDB	50036913
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
50761	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
50762	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
50758	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572
50757	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
50759	Alpha-2B adrenergic receptor	P18089	ADRA2B	Homo sapiens (Human)	450
50760	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462

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