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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL464811
Molecular formula	C32H38ClN5O
IUPAC name	3-chloro-6-[4-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]piperazin-1-yl]-11H-benzo[b][1,4]benzodiazepine
Molecular weight	544.14
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	5.8
Synonyms	BDBM50277099 8-Chloro-11-{4-[4-(3-piperidin-1-yl-propoxy)-benzyl]-piperazin-1-yl}-5H-dibenzo[b,e][1,4]diazepine
Inchi Key	CILDROBPHGWMGB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C32H38ClN5O/c33-26-11-14-30-31(23-26)35-32(28-7-2-3-8-29(28)34-30)38-20-18-37(19-21-38)24-25-9-12-27(13-10-25)39-22-6-17-36-15-4-1-5-16-36/h2-3,7-14,23,34H,1,4-6,15-22,24H2
PubChem CID	135986088
ChEMBL	CHEMBL464811
IUPHAR	N/A
BindingDB	50277099
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
558590	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
558588	D(1B) dopamine receptor	P21918	DRD5	Homo sapiens (Human)	477
558586	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
558591	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
558589	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487
558587	Histamine H3 receptor	Q9Y5N1	HRH3	Homo sapiens (Human)	445

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