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Name | Pyroglutamylated RF-amide peptide receptor |
---|---|
Species | Homo sapiens (Human) |
Gene | QRFPR |
Synonym | QRFP receptor peptide p518 receptor Orexigenic neuropeptide QRFP receptor GPR103 G-protein coupled receptor 103 [ Show all ] |
Disease | N/A |
Length | 431 |
Amino acid sequence | MQALNITPEQFSRLLRDHNLTREQFIALYRLRPLVYTPELPGRAKLALVLTGVLIFALALFGNALVFYVVTRSKAMRTVTNIFICSLALSDLLITFFCIPVTMLQNISDNWLGGAFICKMVPFVQSTAVVTEILTMTCIAVERHQGLVHPFKMKWQYTNRRAFTMLGVVWLVAVIVGSPMWHVQQLEIKYDFLYEKEHICCLEEWTSPVHQKIYTTFILVILFLLPLMVMLILYSKIGYELWIKKRVGDGSVLRTIHGKEMSKIARKKKRAVIMMVTVVALFAVCWAPFHVVHMMIEYSNFEKEYDDVTIKMIFAIVQIIGFSNSICNPIVYAFMNENFKKNVLSAVCYCIVNKTFSPAQRHGNSGITMMRKKAKFSLRENPVEETKGEAFSDGNIEVKLCEQTEEKKKLKRHLALFRSELAENSPLDSGH |
UniProt | Q96P65 |
Protein Data Bank | N/A |
GPCR-HGmod model | Q96P65 |
3D structure model | This predicted structure model is from GPCR-EXP Q96P65. |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL5852 |
IUPHAR | 333 |
DrugBank | N/A |
You can:
GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
8232 | CHEMBL2170391 | C40H54N12O8 | 830.948 | 11 / 11 | -1.4 | No |
442064 | CHEMBL3314361 | C22H25ClN4O | 396.919 | 3 / 0 | 3.5 | Yes |
442119 | CHEMBL3314357 | C27H28N4O | 424.548 | 3 / 0 | 3.8 | Yes |
442223 | CHEMBL3314352 | C21H23BrN4O | 427.346 | 3 / 0 | 3.1 | Yes |
18548 | CHEMBL3287824 | C20H24N2OS | 340.485 | 3 / 1 | 4.3 | Yes |
19355 | CHEMBL1802415 | C49H72N18O11S | 1121.29 | 16 / 17 | -6.1 | No |
555555 | BDBM86225 | C49H72N18O11S | 1121.29 | 16 / 17 | -6.1 | No |
21441 | CHEMBL2170400 | C46H64N12O7 | 897.095 | 10 / 10 | 2.1 | No |
25440 | CHEMBL3287831 | C20H24N2O3S | 372.483 | 4 / 1 | 3.0 | Yes |
26753 | CHEMBL2170389 | C40H54N12O8 | 830.948 | 11 / 12 | -1.4 | No |
26868 | CHEMBL1802370 | C41H55N11O7 | 813.961 | 9 / 10 | 0.4 | No |
442907 | CHEMBL3314358 | C22H25BrN4O | 441.373 | 3 / 0 | 3.4 | Yes |
443284 | CHEMBL3314355 | C23H24N4O | 372.472 | 3 / 0 | 2.4 | Yes |
443417 | CHEMBL3314362 | C23H26ClN3O | 395.931 | 2 / 0 | 4.2 | Yes |
54482 | CHEMBL3287825 | C17H20N2S2 | 316.481 | 3 / 1 | 4.4 | Yes |
555709 | YGGFMRF-amide | C42H57N11O8S | 876.047 | 11 / 11 | 0.2 | No |
60943 | CHEMBL2170397 | C40H54N12O7 | 814.949 | 10 / 10 | -0.3 | No |
63773 | CID 53364285 | C92H137N27O25 | 2021.27 | 30 / 32 | -10.6 | No |
67633 | CHEMBL3287828 | C17H19ClN2S2 | 350.923 | 3 / 1 | 5.0 | Yes |
69250 | CHEMBL3287585 | C20H25ClN2O4S | 424.94 | 6 / 1 | 3.8 | Yes |
69551 | CHEMBL3287814 | C20H23ClN2OS | 374.927 | 3 / 1 | 5.0 | Yes |
78294 | CID 56659504 | C105H158N30O30 | 2320.6 | 35 / 36 | -13.2 | No |
445241 | CHEMBL3314354 | C21H23IN4O | 474.346 | 3 / 0 | 2.8 | Yes |
88871 | CHEMBL1802377 | C51H67N11O9 | 978.165 | 10 / 11 | 1.7 | No |
91045 | CHEMBL3287815 | C21H26N2OS | 354.512 | 3 / 1 | 4.3 | Yes |
93939 | CHEMBL1802366 | C43H59N11O7 | 842.015 | 9 / 10 | 1.2 | No |
100092 | CID 53363631 | C134H201N37O37 | 2922.3 | 42 / 43 | -12.0 | No |
105901 | CHEMBL1802374 | C45H61N11O9 | 900.051 | 10 / 11 | 0.5 | No |
109290 | 600171-70-8 | C126H195N37O37 | 2820.17 | 42 / 45 | -13.2 | No |
113190 | CHEMBL3287821 | C19H24N2OS2 | 360.534 | 4 / 1 | 4.6 | Yes |
119415 | CHEMBL3287818 | C19H23N3OS | 341.473 | 4 / 1 | 3.3 | Yes |
123873 | CHEMBL1939222 | C10H8Cl2N2O2 | 259.086 | 3 / 2 | 2.5 | Yes |
127368 | CHEMBL1802433 | C34H49N11O8 | 739.835 | 10 / 11 | -2.8 | No |
446999 | CHEMBL3314349 | C22H24ClN3O | 381.904 | 2 / 0 | 3.8 | Yes |
556012 | BDBM86227 | C131H215N45O35S | 3012.5 | 42 / 45 | -12.8 | No |
139783 | CHEMBL1802431 | C41H55N11O8 | 829.96 | 10 / 11 | -0.8 | No |
140959 | CHEMBL1802371 | C46H63N11O7 | 882.08 | 9 / 10 | 2.6 | No |
143257 | CHEMBL1802364 | C43H59N11O7 | 842.015 | 9 / 10 | 1.2 | No |
145637 | CHEMBL1802416 | C70H103N21O15 | 1478.73 | 20 / 22 | -3.9 | No |
447596 | CHEMBL3314353 | C22H26N4O | 362.477 | 3 / 0 | 2.5 | Yes |
149819 | CHEMBL1802484 | C42H55N11O9 | 857.97 | 10 / 11 | -0.9 | No |
149834 | 784-90-7 | C12H15N5 | 229.287 | 3 / 2 | 1.5 | Yes |
159598 | CHEMBL3287832 | C18H22N2O2S | 330.446 | 4 / 1 | 3.5 | Yes |
160136 | CHEMBL3287834 | C21H20N2OS | 348.464 | 3 / 1 | 4.6 | Yes |
168926 | CHEMBL1802376 | C48H59N11O10 | 950.067 | 11 / 11 | 1.0 | No |
169704 | CHEMBL3287820 | C18H21NO2S2 | 347.491 | 4 / 1 | 4.5 | Yes |
171592 | CHEMBL2170395 | C40H54N12O8 | 830.948 | 11 / 11 | -1.4 | No |
178832 | BDBM50347825 | C72H106N22O16 | 1535.78 | 21 / 23 | -4.6 | No |
179906 | CHEMBL1802424 | C46H65N13O9 | 944.108 | 12 / 13 | -1.7 | No |
556193 | BDBM86224 | C46H65N13O9 | 944.108 | 12 / 13 | -1.7 | No |
183765 | CHEMBL3287584 | C18H22N2OS2 | 346.507 | 4 / 1 | 4.3 | Yes |
190721 | CHEMBL3287810 | C20H24N2OS | 340.485 | 3 / 1 | 4.3 | Yes |
194598 | CHEMBL3287829 | C18H19F3N2OS2 | 400.478 | 7 / 1 | 5.5 | No |
195504 | CHEMBL1802375 | C47H57N11O9 | 920.041 | 10 / 11 | 0.7 | No |
199550 | CID 56669761 | C118H179N33O33 | 2587.93 | 38 / 39 | -12.4 | No |
199607 | CHEMBL1802379 | C43H60N12O7 | 857.03 | 9 / 9 | 0.2 | No |
203985 | CHEMBL1802421 | C61H94N20O13 | 1315.55 | 18 / 20 | -4.9 | No |
214383 | CHEMBL3287816 | C16H24N2OS | 292.441 | 3 / 1 | 3.1 | Yes |
216277 | CID 56683367 | C137H213N39O37 | 2998.45 | 44 / 42 | -11.2 | No |
450274 | CHEMBL3314350 | C21H23ClN4O | 382.892 | 3 / 0 | 3.0 | Yes |
230735 | CHEMBL1802368 | C42H57N11O7 | 827.988 | 9 / 10 | 0.8 | No |
233561 | CHEMBL2170403 | C44H62N12O8 | 887.056 | 12 / 11 | -0.6 | No |
235966 | CHEMBL1802365 | C43H59N11O7 | 842.015 | 9 / 10 | 1.3 | No |
238624 | CHEMBL2170401 | C43H60N12O8 | 873.029 | 12 / 11 | -0.1 | No |
242918 | CHEMBL2170249 | C42H57N11O7 | 827.988 | 10 / 10 | -0.2 | No |
243494 | CHEMBL2170396 | C42H58N12O9 | 875.001 | 12 / 12 | -1.6 | No |
246035 | CHEMBL1802423 | C52H77N15O10 | 1072.28 | 14 / 15 | -2.1 | No |
556427 | BDBM86228 | C52H77N15O10 | 1072.28 | 14 / 15 | -2.1 | No |
246383 | CHEMBL3287586 | C18H22N2OS2 | 346.507 | 4 / 1 | 4.0 | Yes |
248254 | 1072959-67-1 | C22H24N4O4 | 408.458 | 6 / 2 | 2.5 | Yes |
257849 | CHEMBL1802432 | C41H55N11O8 | 829.96 | 10 / 11 | -0.8 | No |
262782 | CHEMBL3287826 | C18H22N2S2 | 330.508 | 3 / 1 | 4.7 | Yes |
266419 | CHEMBL1802438 | C40H53N11O8 | 815.933 | 10 / 11 | -1.2 | No |
266420 | CHEMBL1802425 | C40H53N11O8 | 815.933 | 10 / 11 | -1.2 | No |
556516 | BDBM86226 | C40H53N11O8 | 815.933 | 10 / 11 | -1.2 | No |
278207 | CHEMBL3287830 | C20H24N2O2S | 356.484 | 4 / 1 | 2.8 | Yes |
281841 | CHEMBL1802422 | C58H89N19O11 | 1228.47 | 16 / 18 | -3.6 | No |
283427 | CHEMBL2170402 | C44H62N12O6 | 855.058 | 10 / 9 | 1.6 | No |
306237 | CHEMBL1802372 | C41H55N11O8 | 829.96 | 10 / 11 | -0.8 | No |
313420 | BDBM50347849 | C125H192N36O36 | 2775.13 | 41 / 40 | -14.1 | No |
313615 | CHEMBL1802378 | C45H55N11O10 | 910.002 | 11 / 11 | 0.1 | No |
317806 | CHEMBL2170390 | C40H54N12O8 | 830.948 | 11 / 12 | -1.4 | No |
320427 | CHEMBL1802369 | C42H57N11O7 | 827.988 | 9 / 10 | 0.8 | No |
323468 | CHEMBL3287823 | C18H22N2OS | 314.447 | 4 / 1 | 4.4 | Yes |
329387 | CID 53363629 | C141H207N37O37 | 3012.43 | 42 / 42 | -10.4 | No |
340079 | CHEMBL3287812 | C18H21BrN2OS2 | 425.403 | 4 / 1 | 5.0 | Yes |
352025 | CHEMBL2170398 | C42H58N12O7 | 843.003 | 10 / 10 | 0.6 | No |
455745 | CHEMBL3314351 | C21H24N4O | 348.45 | 3 / 0 | 2.1 | Yes |
455797 | CHEMBL3314356 | C22H23F3N4O | 416.448 | 6 / 0 | 3.0 | Yes |
355679 | CHEMBL3287833 | C21H26N2O | 322.452 | 2 / 1 | 5.6 | No |
364400 | CHEMBL1802479 | C49H63N11O8 | 934.112 | 10 / 10 | 1.3 | No |
369776 | CHEMBL3287827 | C17H19FN2S2 | 334.471 | 4 / 1 | 4.5 | Yes |
373380 | CHEMBL1802478 | C50H71N13O8 | 982.201 | 12 / 10 | 1.6 | No |
373732 | BDBM50347818 | C127H195N37O37 | 2832.18 | 42 / 41 | -14.7 | No |
376904 | CHEMBL1802380 | C48H58FN11O9 | 952.058 | 11 / 11 | 0.8 | No |
382526 | CHEMBL2170399 | C43H60N12O7 | 857.03 | 10 / 10 | 1.0 | No |
457217 | CHEMBL3314360 | C22H25ClN4O | 396.919 | 3 / 0 | 3.5 | Yes |
406086 | CHEMBL2170392 | C41H56N12O8 | 844.975 | 11 / 11 | -1.0 | No |
406218 | CHEMBL3287819 | C19H23N3OS | 341.473 | 4 / 1 | 3.3 | Yes |
410777 | CHEMBL3287813 | C18H21BrN2OS2 | 425.403 | 4 / 1 | 5.4 | No |
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