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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	784-90-7
Molecular formula	C12H15N5
IUPAC name	2-(4,6,7-trimethylquinazolin-2-yl)guanidine
Molecular weight	229.287
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	1.5
Synonyms	N-(4,6,7-trimethylquinazolin-2-yl)guanidine TOS-BB-1276 1-(4,6,7-trimethylquinazolin-2-yl)guanidine amino(4,6,7-trimethylquinazolin-2-yl)carboxamidine GNF-Pf-1241 HMS2609K23 SCHEMBL3470079 ZX-AN037434 C12H15N5 MolPort-000-870-548 SR-01000493214-1 AKOS000270442 CTK2F9819 R3974 Z57093758 2-(4,6,7-trimethylquinazolin-2-yl)guanidine BAS 00501778 Guanidine, (4,6,7-trimethyl-2-quinazolinyl)- MCULE-6797855535 SMR000284641 9727AE N-(4,6,7-Trimethyl-quinazolin-2-yl)-guanidine STK033079 (4,6,7-trimethyl-quinazolin-2-yl)-guanidine ALBB-021845 DTXSID30386127 SBB041927 ZINC6796972 BDBM50019984 guanidine, N-(4,6,7-trimethyl-2-quinazolinyl)- MLS000688740 SR-01000493214 AC1MEDHI CHEMBL528724 [ Show all ]
Inchi Key	JFQDHSRWWLJCBV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C12H15N5/c1-6-4-9-8(3)15-12(17-11(13)14)16-10(9)5-7(6)2/h4-5H,1-3H3,(H4,13,14,15,16,17)
PubChem CID	2853458
ChEMBL	CHEMBL528724
IUPHAR	N/A
BindingDB	50019984
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
149834	Pyroglutamylated RF-amide peptide receptor	Q96P65	QRFPR	Homo sapiens (Human)	431

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