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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3314358
Molecular formula	C22H25BrN4O
IUPAC name	(5-bromo-1-methylpyrrolo[2,3-c]pyridin-2-yl)-[6-[(dimethylamino)methyl]-4-methyl-3,4-dihydro-1H-isoquinolin-2-yl]methanone
Molecular weight	441.373
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	3.4
Synonyms	(5-Bromo-1-methyl-1H-pyrrolo[2,3-c]pyridin-2-yl){6-[(dimethylamino)methyl]-(+)-4-methyl-3,4-dihydroisoquinolin-2(1H)-yl}methanone BDBM50045838 compound 25e [PMID: 25875054] GTPL9443
Inchi Key	BSGIKRCNMBTGEB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H25BrN4O/c1-14-11-27(13-16-6-5-15(7-18(14)16)12-25(2)3)22(28)19-8-17-9-21(23)24-10-20(17)26(19)4/h5-10,14H,11-13H2,1-4H3
PubChem CID	78210300
ChEMBL	CHEMBL3314358
IUPHAR	9443
BindingDB	50045838
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
442907	Pyroglutamylated RF-amide peptide receptor	Q96P65	QRFPR	Homo sapiens (Human)	431

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