Zhang Lab

National University of Singapore

Home Research COVID-19 Services Publications People Teaching Job Opening News Forum Lab Only

Online Services

●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

GLASS

You can:

Check the GPCR table for details.
Go to the ligand list to see ligands that interacts with this GPCR.
Go to the individual ligand page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

GPCR

Name	Adenosine receptor A2b
Species	Mus musculus (Mouse)
Gene	Adora2b
Synonym	A2b A2B receptor A2BR adenosine receptor A2b
Disease	N/A for non-human GPCRs
Length	332
Amino acid sequence	MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHGCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDSATSNCTELGDGIANKSCCPVTCLFENVVPMSYMVYFNFFGCVLPPLLIMLVIYIKIFMVACKQLQRMELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHKIISRYVLCQAETKGGSGQAGAQSTLSLGL
UniProt	Q60614
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2237
IUPHAR	20
DrugBank	N/A

Known ligands

You can:

Click GLASS IDs to check the association information.
Click ligand names to check details of the ligands.
Download a TSV version of all interaction information.
Download a SDF structure collection of all known ligands.

GLASS ID	Molecule	Formula	Molecular weight	H-bond acceptor / donor	XlogP	Lipinski's druglikeness
6735	MRS 1754	C26H26N6O4	486.532	6 / 2	4.9	Yes
58605	1,7-dimethyl-8-phenyl-3H-purine-2,6-dione	C13H12N4O2	256.265	3 / 1	1.0	Yes
553654	8-Cyclopentyl-1,3-dipropylxanthine	C16H24N4O2	304.394	3 / 1	4.0	Yes
124373	IB-MECA	C18H19IN6O4	510.292	8 / 4	0.9	No
553958	ATL802	C24H22F3N7O3	513.481	9 / 1	2.9	No
138945	2-Cl-IB-Meca	C18H18ClIN6O4	544.734	8 / 4	1.9	No
174531	CVT-6883	C21H21F3N6O2	446.434	7 / 1	4.2	Yes
554341	Cgs 15943	C13H8ClN5O	285.691	5 / 1	2.5	Yes
251184	PSB 603	C24H25ClN6O4S	529.012	7 / 2	3.4	No
291878	CHEMBL2111766	C19H21N5O	335.411	3 / 0	2.5	Yes
554739	(R)-PIA	C19H23N5O4	385.424	8 / 4	2.0	Yes
308492	caffeine	C8H10N4O2	194.194	3 / 0	-0.1	Yes
315329	ENPROFYLLINE	C8H10N4O2	194.194	3 / 2	0.3	Yes
401593	LAS101057	C18H14FN5O	335.342	6 / 1	1.0	Yes
417562	851371-22-7	C17H12N6O	316.324	7 / 1	1.7	Yes
427515	theophylline	C7H8N4O2	180.167	3 / 1	0.0	Yes
555462	BAY 60-6583	C19H17N5O2S	379.438	7 / 2	2.6	Yes

zhanglabzhanggroup.org | +65-6601-1241 | Computing 1, 13 Computing Drive, Singapore 117417