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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	LAS101057
Molecular formula	C18H14FN5O
IUPAC name	N-[5-(3-fluoropyridin-4-yl)-6-pyridin-3-ylpyrazin-2-yl]cyclopropanecarboxamide
Molecular weight	335.342
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	1.0
Synonyms	N-(5-(3-fluoropyridin-4-yl)-6-(pyridin-3-yl)pyrazin-2-yl)cyclopropanecarboxamide ZINC35000463 HY-14390 925676-48-8 N-[5-(3-fluoropyridin-4-yl)-6-pyridin-3-ylpyrazin-2-yl]cyclopropanecarboxamide CHEMBL1672627 BDBM50336977 SCHEMBL3075657 CS-6718 [ Show all ]
Inchi Key	XUYURJQIMYCWBB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H14FN5O/c19-14-9-21-7-5-13(14)17-16(12-2-1-6-20-8-12)23-15(10-22-17)24-18(25)11-3-4-11/h1-2,5-11H,3-4H2,(H,23,24,25)
PubChem CID	16071896
ChEMBL	CHEMBL1672627
IUPHAR	N/A
BindingDB	50336977
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
401592	Adenosine receptor A1	P30542	ADORA1	Homo sapiens (Human)	326
401590	Adenosine receptor A2a	P29274	ADORA2A	Homo sapiens (Human)	412
401591	Adenosine receptor A2b	P29275	ADORA2B	Homo sapiens (Human)	332
401593	Adenosine receptor A2b	Q60614	Adora2b	Mus musculus (Mouse)	332
457618	Adenosine receptor A3	P0DMS8	ADORA3	Homo sapiens (Human)	318

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