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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Adenosine receptor A2b
Species	Mus musculus (Mouse)
Gene	Adora2b
Synonym	A2b A2B receptor A2BR adenosine receptor A2b
Disease	N/A for non-human GPCRs
Length	332
Amino acid sequence	MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHGCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDSATSNCTELGDGIANKSCCPVTCLFENVVPMSYMVYFNFFGCVLPPLLIMLVIYIKIFMVACKQLQRMELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHKIISRYVLCQAETKGGSGQAGAQSTLSLGL
UniProt	Q60614
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2237
IUPHAR	20
DrugBank	N/A

Ligand

Name	CHEMBL2111766
Molecular formula	C19H21N5O
IUPAC name	(8S)-8-ethyl-1,4-dimethyl-2-[(E)-2-phenylethenyl]-7,8-dihydroimidazo[2,1-f]purin-5-one
Molecular weight	335.411
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	2.5
Synonyms	N/A
Inchi Key	RBANSYCEZHILKL-VNDWYCCKSA-N
Inchi ID	InChI=1S/C19H21N5O/c1-4-14-12-24-18(20-14)16-17(23(3)19(24)25)21-15(22(16)2)11-10-13-8-6-5-7-9-13/h5-11,14H,4,12H2,1-3H3/b11-10+/t14-/m0/s1
PubChem CID	71450828
ChEMBL	CHEMBL2111766
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Kb	3700.0 nM	PMID12139454	ChEMBL

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