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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	BAY 60-6583
Molecular formula	C19H17N5O2S
IUPAC name	2-[6-amino-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]pyridin-2-yl]sulfanylacetamide
Molecular weight	379.438
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	2.6
Synonyms	2-({6-amino-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]pyridin-2-yl}sulfanyl)acetamide BAY 60 C6583 D0HE1P BAY-60-6583 SCHEMBL2295404 AKOS024458177 BR 4887; BAY 60 2-[6-Amino-3,5-dicyano-4-(4-cyclopropylmethoxy-phenyl)-pyridin-2-ylsulfanyl]-acetamide GTPL3289 910487-58-0 BAY60-6583 ZINC34641324 B5612 CHEBI:131358 2-[[6-Amino-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]-2-pyridinyl]thio]-acetamide BAY 60-6583, >=98% (HPLC) MolPort-023-277-195 Acetamide, 2-((6-amino-3,5-dicyano-4-(4-(cyclopropylmethoxy)phenyl)-2-pyridinyl)thio)- BR 4887 [ Show all ]
Inchi Key	ZTYHZMAZUWOXNC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H17N5O2S/c20-7-14-17(12-3-5-13(6-4-12)26-9-11-1-2-11)15(8-21)19(24-18(14)23)27-10-16(22)25/h3-6,11H,1-2,9-10H2,(H2,22,25)(H2,23,24)
PubChem CID	11717831
ChEMBL	N/A
IUPHAR	3289
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
555460	Adenosine receptor A1	P30542	ADORA1	Homo sapiens (Human)	326
555464	Adenosine receptor A2a	P29274	ADORA2A	Homo sapiens (Human)	412
555462	Adenosine receptor A2b	Q60614	Adora2b	Mus musculus (Mouse)	332
555463	Adenosine receptor A2b	P29275	ADORA2B	Homo sapiens (Human)	332
555461	Adenosine receptor A3	P0DMS8	ADORA3	Homo sapiens (Human)	318

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