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Name | Gastrin-releasing peptide receptor |
---|---|
Species | Rattus norvegicus (Rat) |
Gene | Grpr |
Synonym | BB2 BB2 receptor gastrin-releasing peptide receptor GRP-preferring bombesin receptor GRP-R |
Disease | N/A for non-human GPCRs |
Length | 384 |
Amino acid sequence | MDPNNCSHLNLEVDPFLSCNNTFNQTLNPPKMDNWFHPGIIYVIPAVYGLIIVIGLIGNITLIKIFCTVKSMRNVPNLFISSLALGDLLLLVTCAPVDASKYLADRWLFGRIGCKLIPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAALIWIVSMLLAIPEAVFSDLHPFHVKDTNQTFISCAPYPHSNELHPKIHSMASFLVFYIIPLSIISVYYYFIARNLIQSAYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTSMLHFITSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPSLLNRSHSTGRSTTCMTSFKSTNPSATFSLINGNICHEGYV |
UniProt | P52500 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL4280 |
IUPHAR | 39 |
DrugBank | N/A |
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GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
6307 | CHEMBL265894 | C56H78N16O10S | 1167.4 | 14 / 13 | 1.5 | No |
14833 | Ranatensin | C61H84N16O13S | 1281.5 | 15 / 14 | 0.4 | No |
20680 | CHEMBL2373070 | C63H98N18O19S | 1443.64 | 25 / 18 | -11.1 | No |
27805 | CHEMBL3142375 | C55H70N14O10 | 1087.25 | 12 / 11 | 1.8 | No |
29697 | CHEMBL2373065 | C88H131N27O27S | 2031.24 | 33 / 26 | -12.6 | No |
32108 | CHEMBL2369819 | C58H76N14O10 | 1129.33 | 12 / 12 | 2.4 | No |
33703 | CHEMBL2373073 | C64H76N14O14S2 | 1329.52 | 17 / 15 | 3.4 | No |
70479 | CHEMBL2373080 | C50H76N16O13S | 1141.32 | 16 / 16 | -2.9 | No |
73669 | CHEMBL3142380 | C48H65N13O10 | 984.129 | 12 / 12 | 0.3 | No |
80205 | CHEMBL3142376 | C52H74N12O9 | 1011.24 | 11 / 11 | 2.6 | No |
84931 | CHEMBL3144532 | C98H110N20O24S3 | 2048.25 | 28 / 24 | 4.1 | No |
86559 | CHEMBL3142382 | C54H76N14O10 | 1081.29 | 12 / 12 | 1.4 | No |
87110 | CHEMBL323166 | C33H37NO5 | 527.661 | 5 / 2 | 7.4 | No |
111416 | CHEMBL3142372 | C54H75N13O11 | 1082.27 | 12 / 12 | 1.9 | No |
117672 | CHEMBL269024 | C53H76N14O10 | 1069.28 | 12 / 13 | 1.7 | No |
128232 | CHEMBL265989 | C50H68N14O8 | 993.184 | 11 / 12 | 2.0 | No |
141867 | CHEMBL2115179 | C52H72N14O10 | 1053.24 | 12 / 12 | 0.7 | No |
141868 | CHEMBL2114155 | C52H72N14O10 | 1053.24 | 12 / 12 | 0.7 | No |
147278 | CHEMBL142356 | C47H68N12O7S | 945.198 | 11 / 11 | 2.7 | No |
153485 | CHEMBL262572 | C54H75N15O9S | 1110.35 | 13 / 12 | 2.2 | No |
170882 | CHEMBL415589 | C51H75N17O11S | 1134.33 | 15 / 14 | -1.6 | No |
448521 | CHEMBL3401468 | C55H80N14O11 | 1113.33 | 13 / 14 | 1.0 | No |
180566 | 123809-85-8 | C72H114N24O17 | 1587.85 | 20 / 22 | -3.9 | No |
184286 | CHEMBL3144556 | C83H111N19O24S2 | 1823.03 | 30 / 21 | -5.4 | No |
194585 | CHEMBL3142371 | C49H66N12O10 | 983.141 | 12 / 10 | 1.3 | No |
203389 | CHEMBL111963 | C16H9BrCl2N4O3 | 456.077 | 4 / 2 | 2.5 | Yes |
212072 | CHEMBL413938 | C53H69N13O9 | 1032.22 | 11 / 12 | 3.0 | No |
216779 | CHEMBL2373074 | C70H88N16O15S2 | 1457.69 | 19 / 17 | 3.0 | No |
217363 | CHEMBL2373067 | C70H88N16O15S2 | 1457.69 | 19 / 17 | 3.0 | No |
223110 | CHEMBL3144547 | C77H119N21O28S | 1818.98 | 36 / 22 | -16.9 | No |
227351 | CHEMBL384085 | C55H75N17O11 | 1150.31 | 14 / 15 | -0.5 | No |
227899 | CHEMBL267138 | C55H77N15O9S | 1124.38 | 13 / 12 | 2.7 | No |
227900 | CHEMBL265360 | C55H77N15O9S | 1124.38 | 13 / 12 | 2.7 | No |
233382 | CHEMBL2373078 | C71H87N17O18S2 | 1530.7 | 21 / 19 | 0.8 | No |
245563 | CHEMBL2373082 | C91H115N18O16S+ | 1749.09 | 20 / 17 | 3.6 | No |
265701 | CHEMBL3144559 | C86H114N20O22S2 | 1844.1 | 29 / 20 | -4.9 | No |
266863 | CHEMBL2370896 | C48H72N12O7 | 929.181 | 9 / 10 | 5.3 | No |
282188 | CHEMBL385969 | C46H67N15O9 | 974.138 | 12 / 13 | -0.8 | No |
283281 | CHEMBL2373083 | C74H108N24O19S | 1669.89 | 22 / 23 | -4.9 | No |
283682 | CHEMBL143860 | C40H61N11O7S | 840.058 | 10 / 10 | 1.6 | No |
289627 | PX9AZU7QPK | C71H110N24O18S | 1619.87 | 21 / 23 | -4.4 | No |
303277 | CHEMBL2373071 | C63H98N18O19S | 1443.64 | 25 / 18 | -11.1 | No |
312851 | CHEMBL2373081 | C49H77N15O10S | 1068.31 | 14 / 14 | -0.8 | No |
319950 | CHEMBL264600 | C49H69N13O9 | 984.173 | 11 / 12 | 1.1 | No |
324039 | CHEMBL3142379 | C48H64N12O11 | 985.113 | 12 / 12 | 0.7 | No |
324380 | CHEMBL3142377 | C49H65N11O11 | 984.125 | 12 / 10 | 1.8 | No |
325841 | CHEMBL2373077 | C77H99N19O19S2 | 1658.87 | 23 / 21 | 0.3 | No |
325918 | CHEMBL3142381 | C52H73N11O10 | 1012.22 | 11 / 11 | 3.1 | No |
334012 | CHEMBL142502 | C38H59N11O6S | 798.021 | 10 / 10 | 1.4 | No |
335169 | CHEMBL385761 | C52H70N14O9 | 1035.22 | 11 / 12 | 2.2 | No |
340843 | CHEMBL2373075 | C56H88N18O14S | 1269.49 | 18 / 18 | -3.4 | No |
353422 | CHEMBL407481 | C53H69N13O9 | 1032.22 | 11 / 12 | 2.5 | No |
354249 | CHEMBL3144557 | C84H109N19O24S2 | 1833.03 | 30 / 21 | -5.1 | No |
354729 | CHEMBL3142378 | C63H77N15O10 | 1204.4 | 13 / 12 | 3.5 | No |
367884 | CHEMBL2373079 | C43H65N13O9S | 940.135 | 12 / 12 | -0.3 | No |
373419 | CHEMBL274937 | C51H68N14O9 | 1021.19 | 12 / 11 | 1.8 | No |
377654 | CHEMBL2373066 | C77H99N19O19S2 | 1658.87 | 23 / 21 | 0.3 | No |
382017 | CHEMBL410615 | C51H71N13O10 | 1026.21 | 11 / 12 | 1.3 | No |
407393 | CHEMBL263778 | C48H69N15O10 | 1016.17 | 12 / 13 | -0.5 | No |
555358 | Neuromedin B | C52H73N15O12S | 1132.31 | 15 / 15 | -1.6 | No |
416913 | CHEMBL3142374 | C59H78N14O10 | 1143.36 | 12 / 12 | 2.7 | No |
417652 | CHEMBL386146 | C49H69N15O11 | 1044.19 | 13 / 12 | -0.7 | No |
417696 | CHEMBL357437 | C44H68N14O9S | 969.177 | 13 / 13 | -1.1 | No |
423908 | CHEMBL415022 | C53H69N13O9 | 1032.22 | 11 / 12 | 2.5 | No |
436818 | CHEMBL3144558 | C91H99N17O20S3 | 1847.07 | 24 / 20 | 6.7 | No |
440204 | CHEMBL142536 | C48H70N12O7S | 959.225 | 11 / 11 | 3.2 | No |
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