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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Gastrin-releasing peptide receptor
Species	Rattus norvegicus (Rat)
Gene	Grpr
Synonym	BB2 BB2 receptor gastrin-releasing peptide receptor GRP-preferring bombesin receptor GRP-R
Disease	N/A for non-human GPCRs
Length	384
Amino acid sequence	MDPNNCSHLNLEVDPFLSCNNTFNQTLNPPKMDNWFHPGIIYVIPAVYGLIIVIGLIGNITLIKIFCTVKSMRNVPNLFISSLALGDLLLLVTCAPVDASKYLADRWLFGRIGCKLIPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAALIWIVSMLLAIPEAVFSDLHPFHVKDTNQTFISCAPYPHSNELHPKIHSMASFLVFYIIPLSIISVYYYFIARNLIQSAYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTSMLHFITSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPSLLNRSHSTGRSTTCMTSFKSTNPSATFSLINGNICHEGYV
UniProt	P52500
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4280
IUPHAR	39
DrugBank	N/A

Ligand

Name	CHEMBL385969
Molecular formula	C46H67N15O9
IUPAC name	(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-acetamido-4-methylpentan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-2-aminopentanediamide
Molecular weight	974.138
Hydrogen bond acceptor	12
Hydrogen bond donor	13
XlogP	-0.8
Synonyms	N/A
Inchi Key	QMZGLLMQGAUZHE-KGAUIJFISA-N
Inchi ID	InChI=1S/C46H67N15O9/c1-24(2)13-31(20-51-27(6)62)57-44(68)36(15-29-18-49-22-54-29)58-39(64)21-53-46(70)40(25(3)4)61-41(65)26(5)56-43(67)35(14-28-17-52-34-10-8-7-9-32(28)34)60-45(69)37(16-30-19-50-23-55-30)59-42(66)33(47)11-12-38(48)63/h7-10,17-19,22-26,31,33,35-37,40,52H,11-16,20-21,47H2,1-6H3,(H2,48,63)(H,49,54)(H,50,55)(H,51,62)(H,53,70)(H,56,67)(H,57,68)(H,58,64)(H,59,66)(H,60,69)(H,61,65)/t26-,31-,33-,35-,36-,37-,40-/m0/s1
PubChem CID	44361729
ChEMBL	CHEMBL385969
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
Release	3.6 %	PMID1469698	ChEMBL
Release	8.2 %	PMID1469698	ChEMBL
Release	14.4 %	PMID1469698	ChEMBL
Release	14.5 %	PMID1469698	ChEMBL

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