You can:
Name | Gastrin-releasing peptide receptor |
---|---|
Species | Rattus norvegicus (Rat) |
Gene | Grpr |
Synonym | BB2 BB2 receptor gastrin-releasing peptide receptor GRP-preferring bombesin receptor GRP-R |
Disease | N/A for non-human GPCRs |
Length | 384 |
Amino acid sequence | MDPNNCSHLNLEVDPFLSCNNTFNQTLNPPKMDNWFHPGIIYVIPAVYGLIIVIGLIGNITLIKIFCTVKSMRNVPNLFISSLALGDLLLLVTCAPVDASKYLADRWLFGRIGCKLIPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAALIWIVSMLLAIPEAVFSDLHPFHVKDTNQTFISCAPYPHSNELHPKIHSMASFLVFYIIPLSIISVYYYFIARNLIQSAYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTSMLHFITSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPSLLNRSHSTGRSTTCMTSFKSTNPSATFSLINGNICHEGYV |
UniProt | P52500 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL4280 |
IUPHAR | 39 |
DrugBank | N/A |
Name | CHEMBL385761 |
---|---|
Molecular formula | C52H70N14O9 |
IUPAC name | (2S)-N-[2-[[(2S)-1-[[(2S)-1-acetamido-4-methylpentan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-2-oxoethyl]-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-acetamido-3-phenylpropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-methylbutanamide |
Molecular weight | 1035.22 |
Hydrogen bond acceptor | 11 |
Hydrogen bond donor | 12 |
XlogP | 2.2 |
Synonyms | N/A |
Inchi Key | UEWFJIVZXYBRKX-PIVAMLDBSA-N |
Inchi ID | InChI=1S/C52H70N14O9/c1-29(2)17-38(25-55-32(6)67)62-49(72)43(20-36-23-53-27-58-36)63-45(69)26-57-52(75)46(30(3)4)66-47(70)31(5)60-48(71)42(19-35-22-56-40-16-12-11-15-39(35)40)64-51(74)44(21-37-24-54-28-59-37)65-50(73)41(61-33(7)68)18-34-13-9-8-10-14-34/h8-16,22-24,27-31,38,41-44,46,56H,17-21,25-26H2,1-7H3,(H,53,58)(H,54,59)(H,55,67)(H,57,75)(H,60,71)(H,61,68)(H,62,72)(H,63,69)(H,64,74)(H,65,73)(H,66,70)/t31-,38-,41+,42-,43-,44-,46-/m0/s1 |
PubChem CID | 44361852 |
ChEMBL | CHEMBL385761 |
IUPHAR | N/A |
BindingDB | N/A |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons. |
Parameter | Value | Reference | Database source |
---|---|---|---|
Release | 2.9 % | PMID1469698 | ChEMBL |
Release | 3.6 % | PMID1469698 | ChEMBL |
Release | 3.7 % | PMID1469698 | ChEMBL |
Release | 16.7 % | PMID1469698 | ChEMBL |
Release | 20.2 % | PMID1469698 | ChEMBL |
zhanglabzhanggroup.org | +65-6601-1241 | Computing 1, 13 Computing Drive, Singapore 117417