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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Gastrin-releasing peptide receptor
Species	Rattus norvegicus (Rat)
Gene	Grpr
Synonym	BB2 BB2 receptor gastrin-releasing peptide receptor GRP-preferring bombesin receptor GRP-R
Disease	N/A for non-human GPCRs
Length	384
Amino acid sequence	MDPNNCSHLNLEVDPFLSCNNTFNQTLNPPKMDNWFHPGIIYVIPAVYGLIIVIGLIGNITLIKIFCTVKSMRNVPNLFISSLALGDLLLLVTCAPVDASKYLADRWLFGRIGCKLIPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAALIWIVSMLLAIPEAVFSDLHPFHVKDTNQTFISCAPYPHSNELHPKIHSMASFLVFYIIPLSIISVYYYFIARNLIQSAYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTSMLHFITSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPSLLNRSHSTGRSTTCMTSFKSTNPSATFSLINGNICHEGYV
UniProt	P52500
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4280
IUPHAR	39
DrugBank	N/A

Ligand

Name	CHEMBL323166
Molecular formula	C33H37NO5
IUPAC name	2-[[(3E)-3-[(3,5-ditert-butyl-4-hydroxyphenyl)methylidene]-1-ethyl-2-oxoindol-5-yl]oxymethyl]benzoic acid
Molecular weight	527.661
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	7.4
Synonyms	2-{3-[1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-meth-(E)-ylidene]-1-ethyl-2-oxo-2,3-dihydro-1H-indol-5-yloxymethyl}-benzoic acid BDBM50280412 CP-70030
Inchi Key	FTTZKWFSFPMEDF-MFKUBSTISA-N
Inchi ID	InChI=1S/C33H37NO5/c1-8-34-28-14-13-22(39-19-21-11-9-10-12-23(21)31(37)38)18-24(28)25(30(34)36)15-20-16-26(32(2,3)4)29(35)27(17-20)33(5,6)7/h9-18,35H,8,19H2,1-7H3,(H,37,38)/b25-15+
PubChem CID	44341807
ChEMBL	CHEMBL323166
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	1500.0 nM	Bioorg. Med. Chem. Lett., (1992) 2:4:333	ChEMBL

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