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Name | C-C chemokine receptor type 5 |
---|---|
Species | Mus musculus (Mouse) |
Gene | Ccr5 |
Synonym | CKR5 CHEMR13 chemokine (C-C motif) receptor 5 (gene/pseudogene) CD195 CCR5 [ Show all ] |
Disease | N/A for non-human GPCRs |
Length | 354 |
Amino acid sequence | MDFQGSVPTYSYDIDYGMSAPCQKINVKQIAAQLLPPLYSLVFIFGFVGNMMVFLILISCKKLKSVTDIYLLNLAISDLLFLLTLPFWAHYAANEWVFGNIMCKVFTGLYHIGYFGGIFFIILLTIDRYLAIVHAVFALKVRTVNFGVITSVVTWAVAVFASLPEIIFTRSQKEGFHYTCSPHFPHTQYHFWKSFQTLKMVILSLILPLLVMVICYSGILHTLFRCRNEKKRHRAVRLIFAIMIVYFLFWTPYNIVLLLTTFQEFFGLNNCSSSNRLDQAMQATETLGMTHCCLNPVIYAFVGEKFRSYLSVFFRKHMVKRFCKRCSIFQQDNPDRASSVYTRSTGEHEVSTGL |
UniProt | P51682 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL3676 |
IUPHAR | N/A |
DrugBank | N/A |
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GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
7491 | CHEMBL106790 | C30H39BrN4O3 | 583.571 | 5 / 1 | 5.3 | No |
459293 | BDBM50115530 | C27H34BrN3O2 | 512.492 | 4 / 0 | 5.4 | No |
29506 | CHEMBL107363 | C30H40BrN3O3 | 570.572 | 5 / 0 | 5.9 | No |
42096 | CHEMBL106299 | C27H35ClN2O | 439.04 | 2 / 0 | 6.2 | No |
47264 | CHEMBL106406 | C27H35IN2O | 530.494 | 2 / 0 | 6.2 | No |
62835 | CHEMBL419735 | C28H37ClN4O3 | 513.079 | 5 / 0 | 4.3 | No |
66705 | CHEMBL1683074 | C25H37F3N4O3 | 498.591 | 9 / 1 | 3.0 | Yes |
68970 | CHEMBL198949 | C23H25ClFN3O2 | 429.92 | 4 / 1 | 3.5 | Yes |
82067 | CHEMBL106209 | C27H33BrN2O2 | 497.477 | 3 / 0 | 5.4 | No |
107692 | CHEMBL443999 | C27H35BrN4O2 | 527.507 | 5 / 0 | 5.0 | No |
109613 | CHEMBL107092 | C28H35F3N2O | 472.596 | 5 / 0 | 6.5 | No |
122585 | CHEMBL317644 | C27H35BrN4O3 | 543.506 | 5 / 0 | 4.3 | No |
124466 | CHEMBL317183 | C34H40BrN3O2 | 602.617 | 4 / 0 | 7.5 | No |
137221 | CHEMBL110809 | C27H35BrN2O | 483.494 | 2 / 0 | 6.3 | No |
145016 | CHEMBL323454 | C27H35BrN2O2 | 499.493 | 3 / 1 | 5.2 | No |
153629 | CHEMBL106767 | C27H34BrN3O3 | 528.491 | 5 / 1 | 5.8 | No |
156033 | CHEMBL320502 | C28H35F3N4O3 | 532.608 | 8 / 0 | 4.2 | No |
162940 | CHEMBL106982 | C28H38N2O3S | 482.683 | 4 / 0 | 4.8 | Yes |
166179 | [4-[4-[(Z)-C-(4-bromophenyl)-N-hydroxy-carbonimidoyl]-1-piperidyl]-4-methyl-1-piperidyl]-(2,6-dimethylphenyl)methanone | C27H34BrN3O2 | 512.492 | 4 / 1 | 5.7 | No |
167923 | CHEMBL331140 | C29H38BrN3O2 | 540.546 | 4 / 0 | 6.4 | No |
167924 | CHEMBL324643 | C29H38BrN3O2 | 540.546 | 4 / 0 | 6.4 | No |
169555 | CHEMBL105784 | C26H32BrClN4O2 | 547.922 | 5 / 1 | 5.8 | No |
180600 | CHEMBL110786 | C28H38N2O | 418.625 | 2 / 0 | 6.0 | No |
189476 | CHEMBL106369 | C28H38N2O2 | 434.624 | 3 / 0 | 5.6 | No |
196815 | CHEMBL105779 | C31H40BrN3O4 | 598.582 | 6 / 0 | 6.3 | No |
206131 | CHEMBL106099 | C27H35ClN4O3 | 499.052 | 5 / 0 | 3.9 | Yes |
213708 | CHEMBL318311 | C29H37F3N4O4 | 562.634 | 9 / 0 | 4.8 | No |
224808 | CHEMBL106507 | C29H38BrN3O3 | 556.545 | 5 / 1 | 5.3 | No |
230960 | CHEMBL110730 | C28H37BrN4O3 | 557.533 | 5 / 1 | 4.4 | No |
247922 | CHEMBL110463 | C28H38N2OS | 450.685 | 3 / 0 | 6.1 | No |
252899 | CHEMBL108959 | C26H33BrN4O2 | 513.48 | 5 / 0 | 4.6 | No |
259062 | CHEMBL108845 | C29H38N2O2 | 446.635 | 3 / 0 | 5.3 | No |
269595 | CHEMBL106264 | C33H40N2O | 480.696 | 2 / 0 | 7.2 | No |
298155 | CHEMBL107999 | C28H37FN4O3 | 496.627 | 6 / 0 | 3.7 | Yes |
307977 | CHEMBL418997 | C31H42BrN3O2 | 568.6 | 4 / 0 | 7.0 | No |
313152 | CHEMBL110270 | C27H36N2O | 404.598 | 2 / 0 | 5.6 | No |
315027 | CHEMBL109158 | C27H35BrN4O2 | 527.507 | 5 / 1 | 5.5 | No |
333142 | CHEMBL105821 | C28H37BrN4O2 | 541.534 | 5 / 0 | 5.3 | No |
334563 | CHEMBL322267 | C27H35BrN4O3 | 543.506 | 5 / 1 | 4.0 | No |
337225 | CHEMBL110871 | C28H37BrN2O | 497.521 | 2 / 0 | 6.6 | No |
337535 | CHEMBL106098 | C27H35BrN4O3 | 543.506 | 5 / 0 | 4.0 | No |
343717 | CHEMBL108569 | C26H33BrN2O2 | 485.466 | 3 / 0 | 5.8 | No |
349328 | naloxone | C19H21NO4 | 327.38 | 5 / 2 | 2.1 | Yes |
349766 | CHEMBL107373 | C27H35BrN4O3 | 543.506 | 5 / 0 | 4.0 | No |
351561 | CHEMBL112760 | C28H36BrN3O2 | 526.519 | 4 / 0 | 6.0 | No |
351563 | CHEMBL324671 | C28H36BrN3O2 | 526.519 | 4 / 0 | 6.0 | No |
360701 | CHEMBL432636 | C28H38N4O5S | 542.695 | 7 / 0 | 2.5 | No |
377105 | CHEMBL2018386 | C28H38F3N5O4 | 565.638 | 8 / 6 | 3.8 | No |
387499 | CHEMBL321413 | C28H32BrF4N3O2 | 598.481 | 8 / 0 | 6.6 | No |
390092 | CHEMBL109008 | C30H40BrN3O2 | 554.573 | 4 / 0 | 6.8 | No |
399278 | CHEMBL317476 | C28H35F3N2O2 | 488.595 | 6 / 0 | 6.8 | No |
400375 | CHEMBL106533 | C29H37F3N4O3 | 546.635 | 8 / 0 | 4.5 | No |
401184 | CHEMBL106558 | C29H40N4O5S | 556.722 | 7 / 0 | 2.9 | No |
402003 | CHEMBL109051 | C35H37FN2O4S | 600.749 | 6 / 0 | 6.8 | No |
403003 | CHEMBL110757 | C28H37BrN4O3 | 557.533 | 5 / 1 | 3.9 | No |
416055 | CHEMBL106573 | C33H38BrN3O2 | 588.59 | 4 / 0 | 7.6 | No |
416484 | CHEMBL106813 | C28H35F3N4O4 | 548.607 | 9 / 0 | 4.5 | No |
422811 | CHEMBL323172 | C27H35BrN4O2 | 527.507 | 5 / 0 | 5.0 | No |
462849 | CID 457678 | C28H37BrN4O3 | 557.533 | 5 / 0 | 4.3 | No |
427714 | Ancriviroc | C28H37BrN4O3 | 557.533 | 5 / 0 | 4.3 | No |
434510 | CHEMBL107154 | C28H35BrN2O | 495.505 | 2 / 0 | 6.8 | No |
438131 | CHEMBL107018 | C26H33BrN4O3 | 529.479 | 5 / 0 | 3.6 | No |
438248 | CHEMBL106247 | C27H35BrN2O | 483.494 | 2 / 0 | 6.3 | No |
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