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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Ancriviroc
Molecular formula	C28H37BrN4O3
IUPAC name	[4-[4-[(Z)-C-(4-bromophenyl)-N-ethoxycarbonimidoyl]piperidin-1-yl]-4-methylpiperidin-1-yl]-(2,4-dimethyl-1-oxidopyridin-1-ium-3-yl)methanone
Molecular weight	557.533
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	4.3
Synonyms	Methanone, (4-bromophenyl)[1'-[(2,4-dimethyl-3-pyridinyl)carbonyl]-4'-methyl[1,4'-bipiperidin]-4-yl]-, O-ethyloxime, (Z)-, N1-oxide & PRO 140 (Anti-CCR5 monoclonal antibody) SCH-C [3H]ancriviroc (4-{(4-Bromo-phenyl)-[(E)-ethoxyimino]-methyl}-4''''-methyl-[1,4'''']bipiperidinyl-1''''-yl)-(2,4-dimethyl-1-oxy-pyridin-3-yl)-methanone D0G6JE Methanone, (4-bromophenyl)(1'-((2,4-dimethyl-3-pyridinyl)carbonyl)-4'-methyl(1,4'-bipiperidin)-4-yl)-, O-ethyloxime, (Z)-, N1-oxide & AOP-RANTES SCH 351125 & AOP-RANTES SCH-C AOP-RANTES [4-[4-[(Z)-C-(4-bromophenyl)-N-ethoxy-carbonimidoyl]-1-piperidyl]-4-methyl-1-piperidyl]-(2,4-dimethyl-1-oxido-pyridin-1-ium-3-yl)methanone 1'-[(2,4-Dimethyl-1-oxidopyridin-3-yl)carbonyl]-4'-methyl-1,4'-bipiperidine Methanone, (4-bromophenyl)[1'-[(2,4-dimethyl-3-pyridinyl)carbonyl]-4'-methyl[1,4'-bipiperidin]-4-yl]-, O-ethyloxime, (Z)-, N1-oxide SCH C SCHEMBL2939134 322WXU4AU2 CHEMBL78535 SC-351125 SCH-C & AOP-RANTES [3H]SCH 351125 (4-{(4-Bromo-phenyl)-[(Z)-ethoxyimino]-methyl}-4''''''''-methyl-[1,4'''''''']bipiperidinyl-1''''''''-yl)-(2,4-dimethyl-1-oxy-pyridin-3-yl)-methanone L023973 Methanone, (4-bromophenyl)(1'-((2,4-dimethyl-3-pyridinyl)carbonyl)-4'-methyl(1,4'-bipiperidin)-4-yl)-, O-ethyloxime, (Z)-, N1-oxide AOP-RANTES SCH 351125 (non-stereospecific) SCH-C cpd {4-[(4-Bromo-phenyl)-ethoxyimino-methyl]-4''''-methyl-[1,4'''']bipiperidinyl-1''''-yl}-(2,4-dimethyl-1-oxy-pyridin-3-yl)-methanone 3-(4-((4-bromophenyl)(ethoxyimino)methyl)-4''''-methyl-1,4''''-bipiperidine-1''''-carbonyl)-1,2,4-trimethylpyridinium BDBM50104931 Methanone, (4-bromophenyl)[1'-[(2,4-dimethyl-3-pyridinyl)carbonyl]-4'-methyl[1,4'-bipiperidin]-4-yl]-, O-ethyloxime, (Z)-, N1-oxide & AOP-RANTES SCH-351125 UNII-322WXU4AU2 (2,4-Dimethyl-1-oxy-pyridin-3-yl)-(4'-methyl-[1,4']bipiperidinyl-1'-yl)-methanone 4-((4-bromophenyl)-(ethoxyimino)methyl)-1'-((2,4-dimethyl-3-pyridinyl)carbonyl)-4'-methyl-1,4'-bipiperidine N-oxide D07KVP SCH 351125 SCH-C & PA14 [3H]Sch-351125 (4-{(4-Bromo-phenyl)-[(Z)-ethoxyimino]-methyl}-4''-methyl-[1,4'']bipiperidinyl-1''-yl)-(2,4-dimethyl-1-oxy-pyridin-3-yl)-methanone AK671/SCH-C LS-183687 Methanone, (4-bromophenyl)(1'-((2,4-dimethyl-3-pyridinyl)carbonyl)-4'-methyl(1,4'-pipiperidin)-4-yl)-, O-ethyloxime, N1-oxide SCH 351125 AOP-RANTES SCH351125 305792-46-5 [ Show all ]
Inchi Key	ZGDKVKUWTCGYOA-URGPHPNLSA-N
Inchi ID	InChI=1S/C28H37BrN4O3/c1-5-36-30-26(22-6-8-24(29)9-7-22)23-11-15-32(16-12-23)28(4)13-18-31(19-14-28)27(34)25-20(2)10-17-33(35)21(25)3/h6-10,17,23H,5,11-16,18-19H2,1-4H3/b30-26+
PubChem CID	9574343
ChEMBL	CHEMBL78535
IUPHAR	802, 804
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
427713	C-C chemokine receptor type 5	P51681	CCR5	Homo sapiens (Human)	352
427714	C-C chemokine receptor type 5	P51682	Ccr5	Mus musculus (Mouse)	354

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