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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL106299
Molecular formula	C27H35ClN2O
IUPAC name	[4-[4-[(4-chlorophenyl)methyl]piperidin-1-yl]-4-methylpiperidin-1-yl]-(2,6-dimethylphenyl)methanone
Molecular weight	439.04
Hydrogen bond acceptor	2
Hydrogen bond donor	0
XlogP	6.2
Synonyms	1,4'-Bipiperidine, 4-[(4-chlorophenyl)methyl]-1'-(2,6-dimethylbenzoyl)-4'-methyl- [4-[4-[(4-chlorophenyl)methyl]-1-piperidyl]-4-methyl-1-piperidyl]-(2,6-dimethylphenyl)methanone AC1LACHY 4-[(4-Chlorophenyl)methyl]-1''-(2,6-dimethylbenzoyl)-4''-methyl-1,4''-bipiperidine [4-[4-[(4-chlorophenyl)methyl]piperidin-1-yl]-4-methylpiperidin-1-yl]-(2,6-dimethylphenyl)methanone BDBM50115534 [4-(4-Chloro-benzyl)-4''-methyl-[1,4'']bipiperidinyl-1''-yl]-(2,6-dimethyl-phenyl)-methanone [ Show all ]
Inchi Key	CHLLENYTSNHZGS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H35ClN2O/c1-20-5-4-6-21(2)25(20)26(31)29-17-13-27(3,14-18-29)30-15-11-23(12-16-30)19-22-7-9-24(28)10-8-22/h4-10,23H,11-19H2,1-3H3
PubChem CID	511294
ChEMBL	CHEMBL106299
IUPHAR	N/A
BindingDB	50115534
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
42096	C-C chemokine receptor type 5	P51682	Ccr5	Mus musculus (Mouse)	354
42097	C-C chemokine receptor type 5	P51681	CCR5	Homo sapiens (Human)	352

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