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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL106264
Molecular formula	C33H40N2O
IUPAC name	(2,6-dimethylphenyl)-[4-methyl-4-[4-[(4-phenylphenyl)methyl]piperidin-1-yl]piperidin-1-yl]methanone
Molecular weight	480.696
Hydrogen bond acceptor	2
Hydrogen bond donor	0
XlogP	7.2
Synonyms	(2,6-dimethylphenyl)-[4-methyl-4-[4-[(4-phenylphenyl)methyl]-1-piperidyl]-1-piperidyl]methanone 1,4'-Bipiperidine, 4-([1,1'-biphenyl]-4-ylmethyl)-1'-(2,6-dimethylbenzoyl)-4'-methyl- BDBM50115545 (2,6-dimethylphenyl)-[4-methyl-4-[4-[(4-phenylphenyl)methyl]piperidin-1-yl]piperidin-1-yl]methanone (4-Biphenyl-4-ylmethyl-4''-methyl-[1,4'']bipiperidinyl-1''-yl)-(2,6-dimethyl-phenyl)-methanone AC1LACI7 [ Show all ]
Inchi Key	PUZLCPWAFDYXST-UHFFFAOYSA-N
Inchi ID	InChI=1S/C33H40N2O/c1-25-8-7-9-26(2)31(25)32(36)34-22-18-33(3,19-23-34)35-20-16-28(17-21-35)24-27-12-14-30(15-13-27)29-10-5-4-6-11-29/h4-15,28H,16-24H2,1-3H3
PubChem CID	511297
ChEMBL	CHEMBL106264
IUPHAR	N/A
BindingDB	50115545
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
269594	C-C chemokine receptor type 5	P51681	CCR5	Homo sapiens (Human)	352
269595	C-C chemokine receptor type 5	P51682	Ccr5	Mus musculus (Mouse)	354

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