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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL106369
Molecular formula	C28H38N2O2
IUPAC name	(2,6-dimethylphenyl)-[4-[4-[(4-methoxyphenyl)methyl]piperidin-1-yl]-4-methylpiperidin-1-yl]methanone
Molecular weight	434.624
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	5.6
Synonyms	(2,6-dimethylphenyl)-[4-[4-[(4-methoxyphenyl)methyl]piperidin-1-yl]-4-methylpiperidin-1-yl]methanone (2,6-Dimethyl-phenyl)-[4-(4-methoxy-benzyl)-4''-methyl-[1,4'']bipiperidinyl-1''-yl]-methanone 1''-(2,6-Dimethylbenzoyl)-4''-methyl-4-[(4-methoxyphenyl)methyl]-1,4''-bipiperidine AC1LACIS (2,6-dimethylphenyl)-[4-[4-[(4-methoxyphenyl)methyl]-1-piperidyl]-4-methyl-1-piperidyl]methanone 1,4'-bipiperidine, 1'-(2,6-dimethylbenzoyl)-4-[(4-methoxyphenyl)methyl]-4'-methyl- BDBM50115523 [ Show all ]
Inchi Key	LKDCAIVJHAMVHC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H38N2O2/c1-21-6-5-7-22(2)26(21)27(31)29-18-14-28(3,15-19-29)30-16-12-24(13-17-30)20-23-8-10-25(32-4)11-9-23/h5-11,24H,12-20H2,1-4H3
PubChem CID	511306
ChEMBL	CHEMBL106369
IUPHAR	N/A
BindingDB	50115523
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
189475	C-C chemokine receptor type 5	P51681	CCR5	Homo sapiens (Human)	352
189476	C-C chemokine receptor type 5	P51682	Ccr5	Mus musculus (Mouse)	354

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