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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL107154
Molecular formula	C28H35BrN2O
IUPAC name	[4-[4-[1-(4-bromophenyl)ethenyl]piperidin-1-yl]-4-methylpiperidin-1-yl]-(2,6-dimethylphenyl)methanone
Molecular weight	495.505
Hydrogen bond acceptor	2
Hydrogen bond donor	0
XlogP	6.8
Synonyms	[4-[4-[1-(4-bromophenyl)vinyl]-1-piperidyl]-4-methyl-1-piperidyl]-(2,6-dimethylphenyl)methanone AC1LACJ1 1,4'-Bipiperidine, 4-[1-(4-bromophenyl)ethenyl]-1'-(2,6-dimethylbenzoyl)-4'-methyl- {4-[1-(4-Bromo-phenyl)-vinyl]-4''-methyl-[1,4'']bipiperidinyl-1''-yl}-(2,6-dimethyl-phenyl)-methanone BDBM50115542 [4-[4-[1-(4-bromophenyl)ethenyl]piperidin-1-yl]-4-methylpiperidin-1-yl]-(2,6-dimethylphenyl)methanone [ Show all ]
Inchi Key	ZPSNELIJNCRWKW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H35BrN2O/c1-20-6-5-7-21(2)26(20)27(32)30-18-14-28(4,15-19-30)31-16-12-24(13-17-31)22(3)23-8-10-25(29)11-9-23/h5-11,24H,3,12-19H2,1-2,4H3
PubChem CID	511309
ChEMBL	CHEMBL107154
IUPHAR	N/A
BindingDB	50115542
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
434509	C-C chemokine receptor type 5	P51681	CCR5	Homo sapiens (Human)	352
434510	C-C chemokine receptor type 5	P51682	Ccr5	Mus musculus (Mouse)	354

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