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GPCR

NameThromboxane A2 receptor
SpeciesRattus norvegicus (Rat)
GeneTbxa2r
Synonymprostanoid TP receptor
TP receptor
TXA2-R
TXR2
DiseaseN/A for non-human GPCRs
Length341
Amino acid sequenceMWLNSTSLGACFRPVNITLQERRAIASPWFAASFCALGLGSNLLALSVLAGARPGAGPRSSFLALLCGLVLTDFLGLLVTGAVVASQHAALLDWRATDPGCRLCHFMGAAMVFFGLCPLLLGAAMAAERFVGITRPFSRPAATSRRAWATVGLVWVGAGTLGLLPLLGLGRYSVQYPGSWCFLTLGAERGDVAFGLMFALLGSVSVGLSLLLNTVSVATLCRVYHAREATQRPRDCEVEMMVQLVGIMVVATVCWMPLLVFILQTLLQTLPVMSPSGQLLRTTERQLLIYLRVATWNQILDPWVYILFRRSVLRRLHPRFTSQLQAVSLHSPPTQAMLSGP
UniProtP34978
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL3156
IUPHAR346
DrugBankN/A

Known ligands

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Total entries: 220
Page:  / 3 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
5962D structureCHEMBL340073C17H24NO4S-338.4425 / 13.5Yes
8662D structureCHEMBL297808C24H26ClNO4S459.9855 / 25.8No
39792D structureCHEMBL117224C23H30N2O4S430.5636 / 23.7Yes
47112D structureCHEMBL158576C33H46N2O4534.7416 / 13.8No
51332D structureCHEMBL65121C17H18ClNO4S367.8445 / 23.2Yes
104282D structureCHEMBL103580C18H18N2O2294.3543 / 23.1Yes
112632D structureCHEMBL64971C25H24ClNO7S2550.0378 / 23.8No
141042D structureCHEMBL298462C23H25ClNNaO5S2518.0156 / 1N/ANo
146072D structureCHEMBL131497C22H20NO4S-394.4655 / 14.5Yes
4653012D structureIfetrobanC25H32N2O5440.546 / 24.0Yes
197482D structureCHEMBL159517C32H44N2O4520.7146 / 13.2No
201382D structureCHEMBL159581C31H40N2O5520.676 / 21.8No
232822D structureCHEMBL161532C31H42N2O5522.6867 / 21.5No
238372D structureTMQ, 5-TrifluoroMeC20H22F3NO5413.3939 / 33.4Yes
253842D structureCHEMBL43772C24H20ClFN2O4S486.9426 / 24.6Yes
263492D structureCHEMBL334501C20H21ClNNaO4S429.8915 / 1N/AN/A
299922D structureCHEMBL161746C32H44N2O6S584.7728 / 21.9No
319862D structureCHEMBL326356C21H27N3O4S417.5247 / 22.3Yes
320392D structureCHEMBL62666C24H23ClFNO4S475.9596 / 25.3No
344082D structureCHEMBL116704C24H26N2O4S438.5426 / 23.8Yes
355062D structureCHEMBL159447C25H26N2O4S450.5536 / 24.4Yes
369302D structureCHEMBL350579C29H37NO4463.6185 / 12.6Yes
369322D structureCHEMBL162589C29H37NO4463.6185 / 12.6Yes
369332D structureCHEMBL161427C29H37NO4463.6185 / 12.6Yes
369352D structureCHEMBL349223C29H37NO4463.6185 / 12.6Yes
374632D structureCHEMBL347812C24H24N2O4S436.5266 / 24.1Yes
388872D structureCHEMBL161252C32H43NO5521.6986 / 22.5No
399782D structureCHEMBL421831C32H42N2O5534.6976 / 21.8No
424222D structureCHEMBL131036C17H15ClNO5S-380.8196 / 13.4Yes
440282D structureCHEMBL430569C22H23ClNNaO5S2503.9886 / 1N/ANo
488812D structureCHEMBL44660C24H21FN2O4S452.56 / 24.0Yes
490632D structureCHEMBL163276C24H24IN3O5S593.4368 / 24.2No
496702D structureCHEMBL47635C25H26N3NaO2S455.5524 / 2N/AN/A
506542D structureCHEMBL335043C16H16NNaO4S2373.4176 / 1N/AN/A
518922D structureCHEMBL114456C24H25ClN2O4S472.9846 / 24.4Yes
536412D structureCHEMBL66136C25H25ClFNO4S489.9866 / 25.6No
561562D structureCHEMBL297989C23H23ClNNaO6S2531.9986 / 1N/ANo
573652D structureCHEMBL132573C19H20NO4S-358.4325 / 13.2Yes
580552D structureDAZMEGRELC16H17N3O2283.3313 / 11.5Yes
586812D structureCHEMBL264516C17H15ClNNaO4S387.815 / 1N/AN/A
597302D structureCHEMBL133420C17H15ClNNaO4S387.815 / 1N/AN/A
617122D structureCHEMBL164109C25H25N3O6S495.558 / 24.2Yes
653562D structureCHEMBL117752C21H23N3O4S413.4926 / 22.3Yes
665672D structureCHEMBL159775C22H20IN3O5S565.3828 / 23.9No
699692D structureCHEMBL131894C19H19ClNNaO4S415.8645 / 1N/AN/A
761282D structureCHEMBL65478C24H24ClNO4S457.9695 / 25.2No
778002D structureCHEMBL105856C23H23FN4O4S470.5197 / 22.7Yes
819542D structureCHEMBL336352C18H17ClNO4S-378.8475 / 14.3Yes
820582D structureCHEMBL117561C24H23ClN2O4S470.9686 / 24.8Yes
842432D structureCHEMBL117294C24H25ClN2O4S472.9846 / 14.3Yes
899512D structureCHEMBL131336C21H23ClNNaO4S443.9185 / 1N/AN/A
939902D structureCHEMBL65779C24H23ClFNO5S491.9587 / 34.1Yes
994012D structureRIDOGRELC18H17F3N2O3366.348 / 13.9Yes
1026642D structureCHEMBL345876C33H46N2O4534.7416 / 13.6No
1071582D structureCHEMBL336352C18H17ClNNaO4S401.8375 / 1N/AN/A
5537992D structureSQ-26655C21H34O4350.4994 / 24.1Yes
1114102D structureCHEMBL162691C29H38N2O4478.6336 / 11.9Yes
1129052D structureCHEMBL162879C25H25N3O6S495.558 / 24.2Yes
1159182D structureCHEMBL47605C24H28NNaO5S2497.66 / 1N/AN/A
1200482D structureCHEMBL115805C23H23NO4S409.55 / 13.7Yes
1200982D structureCHEMBL133420C17H15ClNO4S-364.825 / 13.7Yes
1201112D structureCHEMBL47372C25H23FN2O4S466.5276 / 24.3Yes
1259052D structureCHEMBL117538C22H21ClN2O5S460.9297 / 23.7Yes
1274472D structureCHEMBL119670C24H24N2O3388.4674 / 23.8Yes
1307492D structureCHEMBL131894C19H19ClNO4S-392.8745 / 14.2Yes
1365112D structureCHEMBL340073C17H24NNaO4S361.4325 / 1N/AN/A
1369382D structureCHEMBL161360C32H44N2O6S584.7728 / 21.9No
1382542D structureCHEMBL341221C18H18NO4S-344.4055 / 13.2Yes
1416322D structureCHEMBL116196C23H24N2O4S424.5156 / 23.5Yes
1421302D structureDALTROBANC16H16ClNO4S353.8175 / 22.9Yes
1453112D structureCHEMBL65378C23H23ClN2O4S458.9576 / 24.1Yes
1457302D structureCHEMBL324059C22H30N2O4S418.5526 / 23.6Yes
1495572D structureCHEMBL159936C25H24Cl2N2O4S519.4376 / 25.7No
1511262D structureCHEMBL297315C25H26N3NaO3439.4914 / 2N/AN/A
1517482D structureCHEMBL162641C27H29IN2O4S604.5036 / 25.9No
1590772D structureTMQ, 5,8-DifluoroC19H21F2NO5381.3768 / 32.7Yes
1600732D structureCHEMBL350642C31H42N2O6S570.7458 / 21.9No
1600752D structureCHEMBL345396C31H42N2O6S570.7458 / 21.9No
1637522D structureCHEMBL160091C33H44N2O5548.7246 / 22.1No
1658902D structureCHEMBL2110359C31H41NO5507.6716 / 22.1No
1658922D structureCHEMBL161108C31H41NO5507.6716 / 22.1No
1658952D structureCHEMBL350805C31H41NO5507.6716 / 22.1No
1660992D structureCHEMBL296727C25H25ClN3NaO3473.9334 / 2N/AN/A
1674052D structureCHEMBL132573C19H20NNaO4S381.4225 / 1N/AN/A
1697332D structureCHEMBL418852C21H22ClN3O4S447.9346 / 22.9Yes
1722372D structureCHEMBL115387C23H23FN2O4S442.5057 / 23.6Yes
1726072D structureCHEMBL159272C30H39NO4477.6455 / 13.0Yes
1726092D structureCHEMBL350111C30H39NO4477.6455 / 13.0Yes
1727352D structureCHEMBL131036C17H15ClNNaO5S403.8096 / 1N/AN/A
1796282D structureCHEMBL335043C16H16NO4S2-350.4276 / 13.3Yes
1809702D structureCHEMBL43880C23H24N2O5S440.5146 / 33.4Yes
1811192D structureCHEMBL115636C19H25N3O4S391.4867 / 21.8Yes
1823412D structureCHEMBL65571C25H26ClNO6S2536.0547 / 24.4No
1840512D structureCHEMBL350418C31H41NO5507.6716 / 22.1No
1840532D structureCHEMBL161240C31H41NO5507.6716 / 22.1No
1843832D structureCHEMBL320235C26H26FN3O4S495.5697 / 23.7Yes
1850212D structureCHEMBL158875C30H40N2O5508.6597 / 21.0No
1855822D structureCHEMBL295512C21H19FN4O4S442.4657 / 21.7Yes
1875882D structureCHEMBL45471C24H24ClNO5S473.9685 / 25.2No
1876132D structureCHEMBL132659C19H19ClNNaO4S415.8645 / 1N/AN/A

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