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Name | Thromboxane A2 receptor |
---|---|
Species | Rattus norvegicus (Rat) |
Gene | Tbxa2r |
Synonym | prostanoid TP receptor TP receptor TXA2-R TXR2 |
Disease | N/A for non-human GPCRs |
Length | 341 |
Amino acid sequence | MWLNSTSLGACFRPVNITLQERRAIASPWFAASFCALGLGSNLLALSVLAGARPGAGPRSSFLALLCGLVLTDFLGLLVTGAVVASQHAALLDWRATDPGCRLCHFMGAAMVFFGLCPLLLGAAMAAERFVGITRPFSRPAATSRRAWATVGLVWVGAGTLGLLPLLGLGRYSVQYPGSWCFLTLGAERGDVAFGLMFALLGSVSVGLSLLLNTVSVATLCRVYHAREATQRPRDCEVEMMVQLVGIMVVATVCWMPLLVFILQTLLQTLPVMSPSGQLLRTTERQLLIYLRVATWNQILDPWVYILFRRSVLRRLHPRFTSQLQAVSLHSPPTQAMLSGP |
UniProt | P34978 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL3156 |
IUPHAR | 346 |
DrugBank | N/A |
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GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
596 | ![]() | C17H24NO4S- | 338.442 | 5 / 1 | 3.5 | Yes |
866 | ![]() | C24H26ClNO4S | 459.985 | 5 / 2 | 5.8 | No |
3979 | ![]() | C23H30N2O4S | 430.563 | 6 / 2 | 3.7 | Yes |
4711 | ![]() | C33H46N2O4 | 534.741 | 6 / 1 | 3.8 | No |
5133 | ![]() | C17H18ClNO4S | 367.844 | 5 / 2 | 3.2 | Yes |
10428 | ![]() | C18H18N2O2 | 294.354 | 3 / 2 | 3.1 | Yes |
11263 | ![]() | C25H24ClNO7S2 | 550.037 | 8 / 2 | 3.8 | No |
14104 | ![]() | C23H25ClNNaO5S2 | 518.015 | 6 / 1 | N/A | No |
14607 | ![]() | C22H20NO4S- | 394.465 | 5 / 1 | 4.5 | Yes |
465301 | ![]() | C25H32N2O5 | 440.54 | 6 / 2 | 4.0 | Yes |
19748 | ![]() | C32H44N2O4 | 520.714 | 6 / 1 | 3.2 | No |
20138 | ![]() | C31H40N2O5 | 520.67 | 6 / 2 | 1.8 | No |
23282 | ![]() | C31H42N2O5 | 522.686 | 7 / 2 | 1.5 | No |
23837 | ![]() | C20H22F3NO5 | 413.393 | 9 / 3 | 3.4 | Yes |
25384 | ![]() | C24H20ClFN2O4S | 486.942 | 6 / 2 | 4.6 | Yes |
26349 | ![]() | C20H21ClNNaO4S | 429.891 | 5 / 1 | N/A | N/A |
29992 | ![]() | C32H44N2O6S | 584.772 | 8 / 2 | 1.9 | No |
31986 | ![]() | C21H27N3O4S | 417.524 | 7 / 2 | 2.3 | Yes |
32039 | ![]() | C24H23ClFNO4S | 475.959 | 6 / 2 | 5.3 | No |
34408 | ![]() | C24H26N2O4S | 438.542 | 6 / 2 | 3.8 | Yes |
35506 | ![]() | C25H26N2O4S | 450.553 | 6 / 2 | 4.4 | Yes |
36930 | ![]() | C29H37NO4 | 463.618 | 5 / 1 | 2.6 | Yes |
36932 | ![]() | C29H37NO4 | 463.618 | 5 / 1 | 2.6 | Yes |
36933 | ![]() | C29H37NO4 | 463.618 | 5 / 1 | 2.6 | Yes |
36935 | ![]() | C29H37NO4 | 463.618 | 5 / 1 | 2.6 | Yes |
37463 | ![]() | C24H24N2O4S | 436.526 | 6 / 2 | 4.1 | Yes |
38887 | ![]() | C32H43NO5 | 521.698 | 6 / 2 | 2.5 | No |
39978 | ![]() | C32H42N2O5 | 534.697 | 6 / 2 | 1.8 | No |
42422 | ![]() | C17H15ClNO5S- | 380.819 | 6 / 1 | 3.4 | Yes |
44028 | ![]() | C22H23ClNNaO5S2 | 503.988 | 6 / 1 | N/A | No |
48881 | ![]() | C24H21FN2O4S | 452.5 | 6 / 2 | 4.0 | Yes |
49063 | ![]() | C24H24IN3O5S | 593.436 | 8 / 2 | 4.2 | No |
49670 | ![]() | C25H26N3NaO2S | 455.552 | 4 / 2 | N/A | N/A |
50654 | ![]() | C16H16NNaO4S2 | 373.417 | 6 / 1 | N/A | N/A |
51892 | ![]() | C24H25ClN2O4S | 472.984 | 6 / 2 | 4.4 | Yes |
53641 | ![]() | C25H25ClFNO4S | 489.986 | 6 / 2 | 5.6 | No |
56156 | ![]() | C23H23ClNNaO6S2 | 531.998 | 6 / 1 | N/A | No |
57365 | ![]() | C19H20NO4S- | 358.432 | 5 / 1 | 3.2 | Yes |
58055 | ![]() | C16H17N3O2 | 283.331 | 3 / 1 | 1.5 | Yes |
58681 | ![]() | C17H15ClNNaO4S | 387.81 | 5 / 1 | N/A | N/A |
59730 | ![]() | C17H15ClNNaO4S | 387.81 | 5 / 1 | N/A | N/A |
61712 | ![]() | C25H25N3O6S | 495.55 | 8 / 2 | 4.2 | Yes |
65356 | ![]() | C21H23N3O4S | 413.492 | 6 / 2 | 2.3 | Yes |
66567 | ![]() | C22H20IN3O5S | 565.382 | 8 / 2 | 3.9 | No |
69969 | ![]() | C19H19ClNNaO4S | 415.864 | 5 / 1 | N/A | N/A |
76128 | ![]() | C24H24ClNO4S | 457.969 | 5 / 2 | 5.2 | No |
77800 | ![]() | C23H23FN4O4S | 470.519 | 7 / 2 | 2.7 | Yes |
81954 | ![]() | C18H17ClNO4S- | 378.847 | 5 / 1 | 4.3 | Yes |
82058 | ![]() | C24H23ClN2O4S | 470.968 | 6 / 2 | 4.8 | Yes |
84243 | ![]() | C24H25ClN2O4S | 472.984 | 6 / 1 | 4.3 | Yes |
89951 | ![]() | C21H23ClNNaO4S | 443.918 | 5 / 1 | N/A | N/A |
93990 | ![]() | C24H23ClFNO5S | 491.958 | 7 / 3 | 4.1 | Yes |
99401 | ![]() | C18H17F3N2O3 | 366.34 | 8 / 1 | 3.9 | Yes |
102664 | ![]() | C33H46N2O4 | 534.741 | 6 / 1 | 3.6 | No |
107158 | ![]() | C18H17ClNNaO4S | 401.837 | 5 / 1 | N/A | N/A |
553799 | ![]() | C21H34O4 | 350.499 | 4 / 2 | 4.1 | Yes |
111410 | ![]() | C29H38N2O4 | 478.633 | 6 / 1 | 1.9 | Yes |
112905 | ![]() | C25H25N3O6S | 495.55 | 8 / 2 | 4.2 | Yes |
115918 | ![]() | C24H28NNaO5S2 | 497.6 | 6 / 1 | N/A | N/A |
120048 | ![]() | C23H23NO4S | 409.5 | 5 / 1 | 3.7 | Yes |
120098 | ![]() | C17H15ClNO4S- | 364.82 | 5 / 1 | 3.7 | Yes |
120111 | ![]() | C25H23FN2O4S | 466.527 | 6 / 2 | 4.3 | Yes |
125905 | ![]() | C22H21ClN2O5S | 460.929 | 7 / 2 | 3.7 | Yes |
127447 | ![]() | C24H24N2O3 | 388.467 | 4 / 2 | 3.8 | Yes |
130749 | ![]() | C19H19ClNO4S- | 392.874 | 5 / 1 | 4.2 | Yes |
136511 | ![]() | C17H24NNaO4S | 361.432 | 5 / 1 | N/A | N/A |
136938 | ![]() | C32H44N2O6S | 584.772 | 8 / 2 | 1.9 | No |
138254 | ![]() | C18H18NO4S- | 344.405 | 5 / 1 | 3.2 | Yes |
141632 | ![]() | C23H24N2O4S | 424.515 | 6 / 2 | 3.5 | Yes |
142130 | ![]() | C16H16ClNO4S | 353.817 | 5 / 2 | 2.9 | Yes |
145311 | ![]() | C23H23ClN2O4S | 458.957 | 6 / 2 | 4.1 | Yes |
145730 | ![]() | C22H30N2O4S | 418.552 | 6 / 2 | 3.6 | Yes |
149557 | ![]() | C25H24Cl2N2O4S | 519.437 | 6 / 2 | 5.7 | No |
151126 | ![]() | C25H26N3NaO3 | 439.491 | 4 / 2 | N/A | N/A |
151748 | ![]() | C27H29IN2O4S | 604.503 | 6 / 2 | 5.9 | No |
159077 | ![]() | C19H21F2NO5 | 381.376 | 8 / 3 | 2.7 | Yes |
160073 | ![]() | C31H42N2O6S | 570.745 | 8 / 2 | 1.9 | No |
160075 | ![]() | C31H42N2O6S | 570.745 | 8 / 2 | 1.9 | No |
163752 | ![]() | C33H44N2O5 | 548.724 | 6 / 2 | 2.1 | No |
165890 | ![]() | C31H41NO5 | 507.671 | 6 / 2 | 2.1 | No |
165892 | ![]() | C31H41NO5 | 507.671 | 6 / 2 | 2.1 | No |
165895 | ![]() | C31H41NO5 | 507.671 | 6 / 2 | 2.1 | No |
166099 | ![]() | C25H25ClN3NaO3 | 473.933 | 4 / 2 | N/A | N/A |
167405 | ![]() | C19H20NNaO4S | 381.422 | 5 / 1 | N/A | N/A |
169733 | ![]() | C21H22ClN3O4S | 447.934 | 6 / 2 | 2.9 | Yes |
172237 | ![]() | C23H23FN2O4S | 442.505 | 7 / 2 | 3.6 | Yes |
172607 | ![]() | C30H39NO4 | 477.645 | 5 / 1 | 3.0 | Yes |
172609 | ![]() | C30H39NO4 | 477.645 | 5 / 1 | 3.0 | Yes |
172735 | ![]() | C17H15ClNNaO5S | 403.809 | 6 / 1 | N/A | N/A |
179628 | ![]() | C16H16NO4S2- | 350.427 | 6 / 1 | 3.3 | Yes |
180970 | ![]() | C23H24N2O5S | 440.514 | 6 / 3 | 3.4 | Yes |
181119 | ![]() | C19H25N3O4S | 391.486 | 7 / 2 | 1.8 | Yes |
182341 | ![]() | C25H26ClNO6S2 | 536.054 | 7 / 2 | 4.4 | No |
184051 | ![]() | C31H41NO5 | 507.671 | 6 / 2 | 2.1 | No |
184053 | ![]() | C31H41NO5 | 507.671 | 6 / 2 | 2.1 | No |
184383 | ![]() | C26H26FN3O4S | 495.569 | 7 / 2 | 3.7 | Yes |
185021 | ![]() | C30H40N2O5 | 508.659 | 7 / 2 | 1.0 | No |
185582 | ![]() | C21H19FN4O4S | 442.465 | 7 / 2 | 1.7 | Yes |
187588 | ![]() | C24H24ClNO5S | 473.968 | 5 / 2 | 5.2 | No |
187613 | ![]() | C19H19ClNNaO4S | 415.864 | 5 / 1 | N/A | N/A |
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