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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Thromboxane A2 receptor
Species	Rattus norvegicus (Rat)
Gene	Tbxa2r
Synonym	prostanoid TP receptor TP receptor TXA2-R TXR2
Disease	N/A for non-human GPCRs
Length	341
Amino acid sequence	MWLNSTSLGACFRPVNITLQERRAIASPWFAASFCALGLGSNLLALSVLAGARPGAGPRSSFLALLCGLVLTDFLGLLVTGAVVASQHAALLDWRATDPGCRLCHFMGAAMVFFGLCPLLLGAAMAAERFVGITRPFSRPAATSRRAWATVGLVWVGAGTLGLLPLLGLGRYSVQYPGSWCFLTLGAERGDVAFGLMFALLGSVSVGLSLLLNTVSVATLCRVYHAREATQRPRDCEVEMMVQLVGIMVVATVCWMPLLVFILQTLLQTLPVMSPSGQLLRTTERQLLIYLRVATWNQILDPWVYILFRRSVLRRLHPRFTSQLQAVSLHSPPTQAMLSGP
UniProt	P34978
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3156
IUPHAR	346
DrugBank	N/A

Ligand

Name	CHEMBL340073
Molecular formula	C17H24NO4S-
IUPAC name	2-[2-[(pentylsulfonylamino)methyl]-2,3-dihydro-1H-inden-5-yl]acetate
Molecular weight	338.442
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.5
Synonyms	Sodium; {2-[(pentane-1-sulfonylamino)-methyl]-indan-5-yl}-acetate BDBM50075083
Inchi Key	AAXFWSSVYINXCB-UHFFFAOYSA-M
Inchi ID	InChI=1S/C17H25NO4S/c1-2-3-4-7-23(21,22)18-12-14-9-15-6-5-13(11-17(19)20)8-16(15)10-14/h5-6,8,14,18H,2-4,7,9-12H2,1H3,(H,19,20)/p-1
PubChem CID	91931041
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50075083
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	1400.0 nM	PMID10091692	BindingDB

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