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Name | Thromboxane A2 receptor |
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Species | Rattus norvegicus (Rat) |
Gene | Tbxa2r |
Synonym | prostanoid TP receptor TP receptor TXA2-R TXR2 |
Disease | N/A for non-human GPCRs |
Length | 341 |
Amino acid sequence | MWLNSTSLGACFRPVNITLQERRAIASPWFAASFCALGLGSNLLALSVLAGARPGAGPRSSFLALLCGLVLTDFLGLLVTGAVVASQHAALLDWRATDPGCRLCHFMGAAMVFFGLCPLLLGAAMAAERFVGITRPFSRPAATSRRAWATVGLVWVGAGTLGLLPLLGLGRYSVQYPGSWCFLTLGAERGDVAFGLMFALLGSVSVGLSLLLNTVSVATLCRVYHAREATQRPRDCEVEMMVQLVGIMVVATVCWMPLLVFILQTLLQTLPVMSPSGQLLRTTERQLLIYLRVATWNQILDPWVYILFRRSVLRRLHPRFTSQLQAVSLHSPPTQAMLSGP |
UniProt | P34978 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL3156 |
IUPHAR | 346 |
DrugBank | N/A |
Name | CHEMBL47635 |
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Molecular formula | C25H26N3NaO2S |
IUPAC name | sodium;3-[(4E)-4-(phenylcarbamothioylhydrazinylidene)butyl]-6-propan-2-ylazulene-1-carboxylate |
Molecular weight | 455.552 |
Hydrogen bond acceptor | 4 |
Hydrogen bond donor | 2 |
XlogP | None |
Synonyms | N/A |
Inchi Key | CSRJGNIDCWBRIV-UUXIZDQESA-M |
Inchi ID | InChI=1S/C25H27N3O2S.Na/c1-17(2)18-11-13-21-19(16-23(24(29)30)22(21)14-12-18)8-6-7-15-26-28-25(31)27-20-9-4-3-5-10-20;/h3-5,9-17H,6-8H2,1-2H3,(H,29,30)(H2,27,28,31);/q;+1/p-1/b26-15+; |
PubChem CID | 44291663 |
ChEMBL | CHEMBL47635 |
IUPHAR | N/A |
BindingDB | N/A |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | Partition coefficient log P of this ligand is not available. |
Parameter | Value | Reference | Database source |
---|---|---|---|
IC50 | 590000.0 nM | Bioorg. Med. Chem. Lett., (1993) 3:8:1687 | ChEMBL |
zhanglabzhanggroup.org | +65-6601-1241 | Computing 1, 13 Computing Drive, Singapore 117417