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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Thromboxane A2 receptor
Species	Rattus norvegicus (Rat)
Gene	Tbxa2r
Synonym	prostanoid TP receptor TP receptor TXA2-R TXR2
Disease	N/A for non-human GPCRs
Length	341
Amino acid sequence	MWLNSTSLGACFRPVNITLQERRAIASPWFAASFCALGLGSNLLALSVLAGARPGAGPRSSFLALLCGLVLTDFLGLLVTGAVVASQHAALLDWRATDPGCRLCHFMGAAMVFFGLCPLLLGAAMAAERFVGITRPFSRPAATSRRAWATVGLVWVGAGTLGLLPLLGLGRYSVQYPGSWCFLTLGAERGDVAFGLMFALLGSVSVGLSLLLNTVSVATLCRVYHAREATQRPRDCEVEMMVQLVGIMVVATVCWMPLLVFILQTLLQTLPVMSPSGQLLRTTERQLLIYLRVATWNQILDPWVYILFRRSVLRRLHPRFTSQLQAVSLHSPPTQAMLSGP
UniProt	P34978
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3156
IUPHAR	346
DrugBank	N/A

Ligand

Name	CHEMBL159447
Molecular formula	C25H26N2O4S
IUPAC name	(E)-6-[3-[2-(benzenesulfonamido)ethyl]phenyl]-6-pyridin-3-ylhex-5-enoic acid
Molecular weight	450.553
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	4.4
Synonyms	BDBM50391325
Inchi Key	BXVLOKOSLGIICL-ZMOGYAJESA-N
Inchi ID	InChI=1S/C25H26N2O4S/c28-25(29)14-5-4-13-24(22-10-7-16-26-19-22)21-9-6-8-20(18-21)15-17-27-32(30,31)23-11-2-1-3-12-23/h1-3,6-13,16,18-19,27H,4-5,14-15,17H2,(H,28,29)/b24-13+
PubChem CID	44374895
ChEMBL	CHEMBL159447
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Kd	15.85 nM	Bioorg. Med. Chem. Lett., (1991) 1:12:699	ChEMBL

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