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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	TMQ, 5,8-Difluoro
Molecular formula	C19H21F2NO5
IUPAC name	5,8-difluoro-1-[(3,4,5-trimethoxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol
Molecular weight	381.376
Hydrogen bond acceptor	8
Hydrogen bond donor	3
XlogP	2.7
Synonyms	PDSP1_000593 PDSP2_000590 CHEMBL358648 BDBM82498
Inchi Key	JSUCHNUEMCJTOS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H21F2NO5/c1-25-12-7-9(8-13(26-2)19(12)27-3)6-11-14-10(4-5-22-11)15(20)17(23)18(24)16(14)21/h7-8,11,22-24H,4-6H2,1-3H3
PubChem CID	10339796
ChEMBL	CHEMBL358648
IUPHAR	N/A
BindingDB	82498
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
159080	Beta-1 adrenergic receptor	P08588	ADRB1	Homo sapiens (Human)	477
159079	Beta-2 adrenergic receptor	Q8K4Z4	Adrb2	Cavia porcellus (Guinea pig)	418
556083	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
159077	Thromboxane A2 receptor	P34978	Tbxa2r	Rattus norvegicus (Rat)	341
159078	Thromboxane A2 receptor	P21731	TBXA2R	Homo sapiens (Human)	343

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