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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	TMQ, 5-TrifluoroMe
Molecular formula	C20H22F3NO5
IUPAC name	5-(trifluoromethyl)-1-[(3,4,5-trimethoxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol
Molecular weight	413.393
Hydrogen bond acceptor	9
Hydrogen bond donor	3
XlogP	3.4
Synonyms	BDBM82504 PDSP1_000601 PDSP2_000598 CHEMBL143645
Inchi Key	BHLICJAYUSKMQT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H22F3NO5/c1-27-15-7-10(8-16(28-2)19(15)29-3)6-13-12-9-14(25)18(26)17(20(21,22)23)11(12)4-5-24-13/h7-9,13,24-26H,4-6H2,1-3H3
PubChem CID	15133335
ChEMBL	CHEMBL143645
IUPHAR	N/A
BindingDB	82504
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
23835	Beta-2 adrenergic receptor	Q8K4Z4	Adrb2	Cavia porcellus (Guinea pig)	418
23836	Thromboxane A2 receptor	P21731	TBXA2R	Homo sapiens (Human)	343
23837	Thromboxane A2 receptor	P34978	Tbxa2r	Rattus norvegicus (Rat)	341

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