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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Thromboxane A2 receptor
Species	Rattus norvegicus (Rat)
Gene	Tbxa2r
Synonym	prostanoid TP receptor TP receptor TXA2-R TXR2
Disease	N/A for non-human GPCRs
Length	341
Amino acid sequence	MWLNSTSLGACFRPVNITLQERRAIASPWFAASFCALGLGSNLLALSVLAGARPGAGPRSSFLALLCGLVLTDFLGLLVTGAVVASQHAALLDWRATDPGCRLCHFMGAAMVFFGLCPLLLGAAMAAERFVGITRPFSRPAATSRRAWATVGLVWVGAGTLGLLPLLGLGRYSVQYPGSWCFLTLGAERGDVAFGLMFALLGSVSVGLSLLLNTVSVATLCRVYHAREATQRPRDCEVEMMVQLVGIMVVATVCWMPLLVFILQTLLQTLPVMSPSGQLLRTTERQLLIYLRVATWNQILDPWVYILFRRSVLRRLHPRFTSQLQAVSLHSPPTQAMLSGP
UniProt	P34978
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3156
IUPHAR	346
DrugBank	N/A

Ligand

Name	CHEMBL162879
Molecular formula	C25H25N3O6S
IUPAC name	(E)-6-[3-[2-[(4-nitrophenyl)sulfonylamino]ethyl]phenyl]-6-pyridin-3-ylhex-5-enoic acid
Molecular weight	495.55
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	4.2
Synonyms	BDBM50391321
Inchi Key	HEMGORMJZTVDGN-KTZMUZOWSA-N
Inchi ID	InChI=1S/C25H25N3O6S/c29-25(30)9-2-1-8-24(21-7-4-15-26-18-21)20-6-3-5-19(17-20)14-16-27-35(33,34)23-12-10-22(11-13-23)28(31)32/h3-8,10-13,15,17-18,27H,1-2,9,14,16H2,(H,29,30)/b24-8+
PubChem CID	44374857
ChEMBL	CHEMBL162879
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Kd	3.981 nM	Bioorg. Med. Chem. Lett., (1991) 1:12:699	ChEMBL

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