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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Thromboxane A2 receptor
Species	Rattus norvegicus (Rat)
Gene	Tbxa2r
Synonym	prostanoid TP receptor TP receptor TXA2-R TXR2
Disease	N/A for non-human GPCRs
Length	341
Amino acid sequence	MWLNSTSLGACFRPVNITLQERRAIASPWFAASFCALGLGSNLLALSVLAGARPGAGPRSSFLALLCGLVLTDFLGLLVTGAVVASQHAALLDWRATDPGCRLCHFMGAAMVFFGLCPLLLGAAMAAERFVGITRPFSRPAATSRRAWATVGLVWVGAGTLGLLPLLGLGRYSVQYPGSWCFLTLGAERGDVAFGLMFALLGSVSVGLSLLLNTVSVATLCRVYHAREATQRPRDCEVEMMVQLVGIMVVATVCWMPLLVFILQTLLQTLPVMSPSGQLLRTTERQLLIYLRVATWNQILDPWVYILFRRSVLRRLHPRFTSQLQAVSLHSPPTQAMLSGP
UniProt	P34978
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3156
IUPHAR	346
DrugBank	N/A

Ligand

Name	DAZMEGREL
Molecular formula	C16H17N3O2
IUPAC name	3-[3-(imidazol-1-ylmethyl)-2-methylindol-1-yl]propanoic acid
Molecular weight	283.331
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	1.5
Synonyms	UK 38485 1H-Indole-1-propanoicacid, 3-(1H-imidazol-1-ylmethyl)-2-methyl- 31340R8PVU CCG-20521 Dazmegrel [USAN:BAN:INN] EU-0045204 SCHEMBL154037 ST50898364 UNII-31340R8PVU 3-(3-Imidazol-1-ylmethyl-2-methyl-indol-1-yl)-propionic acid AC1Q2FAS CTK2H7526 Dazmegrelum [Latin] MCULE-1200400346 Tox21_111966_1 3-[3-(imidazol-1-ylmethyl)-2-methylindol-1-yl]propanoic acid CAS-76894-77-4 DSSTox_RID_81507 NCGC00160660-02 UK-38,485 3-(1H-imidazol-1-ylmethyl)-2-methyl-1H-Indole-1-propanoic acid 76894-77-4 Dazmegrel [USAN:INN:BAN] FT-0746556 SR-01000082437 STK094650 ZINC35877948 3-(Imidazol-1-ylmethyl)-2-methylindole-1-propionic acid AKOS005395464 D03661 DSSTox_CID_26281 MolPort-002-320-893 UK 38,485 1H-Indole-1-propanoic acid, 3-(1H-imidazol-1-ylmethyl)-2-methyl- 3-[3-(imidazolylmethyl)-2-methylindolyl]propanoic acid CBDivE_000516 Dazmegrel (USAN/INN) DTXSID9046281 Oprea1_040141 UK-38485 3-(1H-imidazole-1-yl-methyl)-2-methyl-1H-indole-1-propanoic acid AC1L1F59 CHEMBL283656 Dazmegrelum LS-177314 SR-01000082437-1 Tox21_111966 3-[3-(1H-imidazol-1-ylmethyl)-2-methyl-1H-indol-1-yl]propanoic acid BDBM50000317 DA-03506 DSSTox_GSID_46281 NCGC00160660-01 [ Show all ]
Inchi Key	DEQLGSOHGTZKFB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H17N3O2/c1-12-14(10-18-9-7-17-11-18)13-4-2-3-5-15(13)19(12)8-6-16(20)21/h2-5,7,9,11H,6,8,10H2,1H3,(H,20,21)
PubChem CID	53555
ChEMBL	CHEMBL283656
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Kd	<1000.0 nM	Bioorg. Med. Chem. Lett., (1996) 6:14:1691	ChEMBL

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