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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Skf 83566
Molecular formula	C17H18BrNO
IUPAC name	8-bromo-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol
Molecular weight	332.241
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	4.0
Synonyms	BRD-A52588987-004-04-1 GTPL944 SK-83566 7-bromo-3-methyl-1-phenyl-1,2,4,5-tetrahydro-3-benzazepin-8-ol 8-bromo-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol AC1Q25IF PDSP1_000503 SKF-83566 8-Bromo-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol Biomol-NT_000061 D0LR8X SK&F 83566 1H-3-Benzazepin-7-ol, 8-bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl-, (R)- 7-Bromo-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine 99295-33-7 C17H19Br2NO LS-178232 8-Bromo-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-ol AKOS027307785 CHEMBL324017 PDSP2_000501 XFTVOHWWEQGXLS-UHFFFAOYSA-N 1H-3-Benzazepin-7-ol, 8-bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl- 8-Bromo-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SKF 83566) BPBio1_001347 DTXSID8043816 SK&F-83566 8-bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1h-3-benzazepin-7-ol AC1L1B1K CHEBI:91747 NCGC00025222-02 SKF-83556 8-Bromo-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-ol # BDBM50010301 CTK5H6430 SCHEMBL20415945 Z3070 1H-3-Benzazepin-7-ol, 8-bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl-, (+/-)- [ Show all ]
Inchi Key	XFTVOHWWEQGXLS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H18BrNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3
PubChem CID	1243
ChEMBL	CHEMBL324017
IUPHAR	944
BindingDB	50010301
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
390714	5-hydroxytryptamine receptor 5A	P35364	Htr5a	Rattus norvegicus (Rat)	357
390713	5-hydroxytryptamine receptor 5B	P35365	Htr5b	Rattus norvegicus (Rat)	370
390711	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
390715	D(1B) dopamine receptor	P21918	DRD5	Homo sapiens (Human)	477
390712	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443

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