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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL71798
Molecular formula	C24H31N3O3
IUPAC name	(1R)-1-[2-[4-(4-methoxyphenyl)piperazin-1-yl]ethyl]-N-methyl-3,4-dihydro-1H-isochromene-6-carboxamide
Molecular weight	409.53
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	2.9
Synonyms	DTXSID00442608 RT-015079 (R)-1-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-isochroman-6-carboxylic acid methylamide J-012075 BDBM50064787 SCHEMBL8549606 CTK8E8480 187665-60-7 PNU 109291 [ Show all ]
Inchi Key	UDLSEQDYARNKTL-HSZRJFAPSA-N
Inchi ID	InChI=1S/C24H31N3O3/c1-25-24(28)19-3-8-22-18(17-19)10-16-30-23(22)9-11-26-12-14-27(15-13-26)20-4-6-21(29-2)7-5-20/h3-8,17,23H,9-16H2,1-2H3,(H,25,28)/t23-/m1/s1
PubChem CID	10621491
ChEMBL	CHEMBL71798
IUPHAR	N/A
BindingDB	50064787
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
334202	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
334201	5-hydroxytryptamine receptor 1B	Q9N2B7	HTR1B	Gorilla gorilla gorilla (Western lowland gorilla)	390
334205	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
334204	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
334203	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443

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