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Name | 5-hydroxytryptamine receptor 1B |
---|---|
Species | Gorilla gorilla gorilla (Western lowland gorilla) |
Gene | HTR1B |
Synonym | 5-HT-1B 5-HT1B Serotonin receptor 1B |
Disease | N/A for non-human GPCRs |
Length | 390 |
Amino acid sequence | MEEPGAQCAPPXPAGSETWVPQANLSSAPSQNCSAKDYIYQDSIALPWKVLLVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISISLPPFFWRQAKAEEEVSECVVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRILKQTPNRTGKRLTRAQLITDSPGSTSSVTSINSRVPDVPSESGSPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAIFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCTS |
UniProt | Q9N2B7 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL2304408 |
IUPHAR | N/A |
DrugBank | N/A |
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GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
128783 | CHEMBL71724 | C22H28N2O2 | 352.478 | 4 / 0 | 3.6 | Yes |
175640 | sumatriptan | C14H21N3O2S | 295.401 | 4 / 2 | 0.9 | Yes |
237677 | CHEMBL71907 | C23H29N3O3 | 395.503 | 5 / 1 | 2.5 | Yes |
237682 | CHEMBL71635 | C23H29N3O3 | 395.503 | 5 / 1 | 2.5 | Yes |
237688 | CHEMBL69385 | C23H29N3O3 | 395.503 | 5 / 1 | 2.5 | Yes |
334201 | CHEMBL71798 | C24H31N3O3 | 409.53 | 5 / 1 | 2.9 | Yes |
334207 | PNU-109291 | C24H31N3O3 | 409.53 | 5 / 1 | 2.9 | Yes |
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